Literature DB >> 11922720

Malignant astrocytoma of the conus medullaris treated by spinal cordectomy.

Kazuhiko Kyoshima1, Kiyoshi Ito, Akihiko Tanabe, Tomomi Iwashita, Tetsuya Goto, Atsushi Sato, Jun Nakayama.   

Abstract

We present a case of malignant astrocytoma of the conus medullaris in a 48-year-old man treated by spinal cordectomy. Preoperative examination revealed a tumor at the T12 to L1 level, and intraparenchymal invasion up to T8. The spinal cord was amputated caudally to the root entry zones of the T9 sensory roots. Additional cordectomies were repeated three times because of tumor infiltration at the cut end. At each procedure, the cord was segmentally transected just caudal to the root entry zones of the p reserving-aid sensory roots to minimize the neural deficit. The final transected level was between T3 and T4, and the cut end did not pathologically reveal any tumor invasion. However, the patient died from tumor recurrence and dissemination. Although the attempt to control the tumor by long segment cordectomy was unsuccessful, spinal cordectomy with wide margin may be a possible treatment for patients with malignant astrocytoma of the conus medullaris presenting with complete deficit below the lesion a nd no dissemination, if in an early stage. Copyright 2002, Elsevier Science Ltd. All rights reserved.

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Year:  2002        PMID: 11922720     DOI: 10.1054/jocn.2001.0929

Source DB:  PubMed          Journal:  J Clin Neurosci        ISSN: 0967-5868            Impact factor:   1.961


  4 in total

1.  Prognostic factors and survival in primary malignant astrocytomas of the spinal cord: a population-based analysis from 1973 to 2007.

Authors:  Hadie Adams; Javier Avendaño; Shaan M Raza; Ziya L Gokaslan; George I Jallo; Alfredo Quiñones-Hinojosa
Journal:  Spine (Phila Pa 1976)       Date:  2012-05-20       Impact factor: 3.468

2.  Hypofractionated radiotherapy boost for dose escalation as a treatment option for high-grade spinal cord astrocytic tumor.

Authors:  Norio Katoh; Hiroki Shirato; Hidefumi Aoyama; Rikiya Onimaru; Keishiro Suzuki; Kazutoshi Hida; Kazuo Miyasaka; Yoshinobu Iwasaki
Journal:  J Neurooncol       Date:  2005-11-29       Impact factor: 4.130

3.  Clinical outcomes and a therapeutic indication of intramedullary spinal cord astrocytoma.

Authors:  Narihito Nagoshi; Osahiko Tsuji; Satoshi Suzuki; Satoshi Nori; Mitsuru Yagi; Eijiro Okada; Hajime Okita; Nobuyuki Fujita; Ken Ishii; Morio Matsumoto; Masaya Nakamura; Kota Watanabe
Journal:  Spinal Cord       Date:  2021-07-26       Impact factor: 2.772

4.  Cordectomy for intramedullary spinal cord glioblastoma with a 12-year survival.

Authors:  Stephanus Viljoen; Patrick W Hitchon; Raheel Ahmed; Patricia A Kirby
Journal:  Surg Neurol Int       Date:  2014-06-25
  4 in total

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