Literature DB >> 11919689

Early embryonic lethality in mice deficient in the p110beta catalytic subunit of PI 3-kinase.

Lei Bi1, Ichiro Okabe, David J Bernard, Robert L Nussbaum.   

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Year:  2002        PMID： 11919689     DOI： 10.1007/BF02684023

Source DB:  PubMed          Journal:  Mamm Genome        ISSN： 0938-8990            Impact factor:   2.957


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  22 in total

1.  Phosphatidylinositol-3-OH kinases are Rab5 effectors.

Authors:  S Christoforidis; M Miaczynska; K Ashman; M Wilm; L Zhao; S C Yip; M D Waterfield; J M Backer; M Zerial
Journal:  Nat Cell Biol       Date:  1999-08       Impact factor: 28.824

Review 2.  Structure and function of phosphoinositide 3-kinases.

Authors:  M P Wymann; L Pirola
Journal:  Biochim Biophys Acta       Date:  1998-12-08

3.  Ethanol precipitation of DNA with linear polyacrylamide as carrier.

Authors:  C Gaillard; F Strauss
Journal:  Nucleic Acids Res       Date:  1990-01-25       Impact factor: 16.971

Review 4.  Synergistic activation of a family of phosphoinositide 3-kinase via G-protein coupled and tyrosine kinase-related receptors.

Authors:  T Katada; H Kurosu; T Okada; T Suzuki; N Tsujimoto; S Takasuga; K Kontani; O Hazeki; M Ui
Journal:  Chem Phys Lipids       Date:  1999-04       Impact factor: 3.329

Review 5.  Synthesis and function of 3-phosphorylated inositol lipids.

Authors:  B Vanhaesebroeck; S J Leevers; K Ahmadi; J Timms; R Katso; P C Driscoll; R Woscholski; P J Parker; M D Waterfield
Journal:  Annu Rev Biochem       Date:  2001       Impact factor: 23.643

6.  P110delta, a novel phosphoinositide 3-kinase in leukocytes.

Authors:  B Vanhaesebroeck; M J Welham; K Kotani; R Stein; P H Warne; M J Zvelebil; K Higashi; S Volinia; J Downward; M D Waterfield
Journal:  Proc Natl Acad Sci U S A       Date:  1997-04-29       Impact factor: 11.205

7.  A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002).

Authors:  C J Vlahos; W F Matter; K Y Hui; R F Brown
Journal:  J Biol Chem       Date:  1994-02-18       Impact factor: 5.157

8.  Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses.

Authors:  A Arcaro; M P Wymann
Journal:  Biochem J       Date:  1993-12-01       Impact factor: 3.857

9.  Fibroblast growth factor receptor 3 is a negative regulator of bone growth.

Authors:  C Deng; A Wynshaw-Boris; F Zhou; A Kuo; P Leder
Journal:  Cell       Date:  1996-03-22       Impact factor: 41.582

10.  The PI 3-kinase isoforms p110(alpha) and p110(beta) have differential roles in PDGF- and insulin-mediated signaling.

Authors:  R Hooshmand-Rad; L Hájková; P Klint; R Karlsson; B Vanhaesebroeck; L Claesson-Welsh; C H Heldin
Journal:  J Cell Sci       Date:  2000-01       Impact factor: 5.285
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  120 in total

1.  A constitutively activated form of the p110beta isoform of PI3-kinase induces prostatic intraepithelial neoplasia in mice.

Authors:  Sang Hyun Lee; George Poulogiannis; Saumyadipta Pyne; Shidong Jia; Lihua Zou; Sabina Signoretti; Massimo Loda; Lewis Clayton Cantley; Thomas M Roberts
Journal:  Proc Natl Acad Sci U S A       Date:  2010-06-01       Impact factor: 11.205

2.  Development of a peptide-drug conjugate for prostate cancer therapy.

Authors:  Wanyi Tai; Ravi S Shukla; Bin Qin; Benyi Li; Kun Cheng
Journal:  Mol Pharm       Date:  2011-05-03       Impact factor: 4.939

3.  Essential, nonredundant role for the phosphoinositide 3-kinase p110delta in signaling by the B-cell receptor complex.

Authors:  Shiann-Tarng Jou; Nick Carpino; Yutaka Takahashi; Roland Piekorz; Jyh-Rong Chao; Neena Carpino; Demin Wang; James N Ihle
Journal:  Mol Cell Biol       Date:  2002-12       Impact factor: 4.272

Review 4.  The B-cell receptor signaling pathway as a therapeutic target in CLL.

Authors:  Jennifer A Woyach; Amy J Johnson; John C Byrd
Journal:  Blood       Date:  2012-06-19       Impact factor: 22.113

5.  Nuclear phosphoinositide 3-kinase beta controls double-strand break DNA repair.

Authors:  Amit Kumar; Oscar Fernandez-Capetillo; Oscar Fernadez-Capetillo; Ana C Carrera
Journal:  Proc Natl Acad Sci U S A       Date:  2010-04-05       Impact factor: 11.205

6.  Biased binding of class IA phosphatidyl inositol 3-kinase subunits to inducible costimulator (CD278).

Authors:  Yenny Y Acosta; Maria Paz Zafra; Gloria Ojeda; Ilaria Seren Bernardone; Umberto Dianzani; Pilar Portolés; Jose M Rojo
Journal:  Cell Mol Life Sci       Date:  2010-12-28       Impact factor: 9.261

7.  PI3Kα inactivation in leptin receptor cells increases leptin sensitivity but disrupts growth and reproduction.

Authors:  David Garcia-Galiano; Beatriz C Borges; Jose Donato; Susan J Allen; Nicole Bellefontaine; Mengjie Wang; Jean J Zhao; Kenneth M Kozloff; Jennifer W Hill; Carol F Elias
Journal:  JCI Insight       Date:  2017-12-07

8.  Mice Carrying a Dominant-Negative Human PI3K Mutation Are Protected From Obesity and Hepatic Steatosis but Not Diabetes.

Authors:  Marie H Solheim; Jonathon N Winnay; Thiago M Batista; Anders Molven; Pål R Njølstad; C Ronald Kahn
Journal:  Diabetes       Date:  2018-05-03       Impact factor: 9.461

Review 9.  PI3K signaling in glioma--animal models and therapeutic challenges.

Authors:  Christine K Cheng; Qi-Wen Fan; William A Weiss
Journal:  Brain Pathol       Date:  2009-01       Impact factor: 6.508

10.  The PTEN/PI3K pathway governs normal vascular development and tumor angiogenesis.

Authors:  Koichi Hamada; Takehiko Sasaki; Pandelakis A Koni; Miyuki Natsui; Hiroyuki Kishimoto; Junko Sasaki; Nobuyuki Yajima; Yasuo Horie; Go Hasegawa; Makoto Naito; Jun-Ichi Miyazaki; Toshio Suda; Hiroshi Itoh; Kazuwa Nakao; Tak Wah Mak; Toru Nakano; Akira Suzuki
Journal:  Genes Dev       Date:  2005-08-17       Impact factor: 11.361
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