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Literature DB >> 11919502

Polyphenolic antioxidant (-)-epigallocatechin-3-gallate from green tea as a candidate anti-HIV agent.

Gianfranco Fassina¹, Anna Buffa, Roberto Benelli, Oliviero E Varnier, Douglas M Noonan, Adriana Albini.

Abstract

Epigallocatechin-3-gallate (EGCG), one of the components of green tea, has been suggested to have antiviral activity. To determine the effects of EGCG on HIV infection, peripheral blood lymphocytes were incubated with either LAI/IIIB or Bal HIV strains and increasing concentrations of EGCG. EGCG strongly inhibited the replication of both virus strains as determined by reverse transcriptase and p24 assays on the cell supernatants.

Entities: Chemical Disease Gene

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Year: 2002 PMID： 11919502 DOI： 10.1097/00002030-200204120-00020

Source DB: PubMed Journal: AIDS ISSN： 0269-9370 Impact factor: 4.177

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Cited

30 in total

1. Tea polyphenols exerts anti-hepatitis B virus effects in a stably HBV-transfected cell line.

Authors: Pian Ye; Shuling Zhang; Lei Zhao; Jihua Dong; Shenghua Jie; Ran Pang; Shuli Li
Journal: J Huazhong Univ Sci Technolog Med Sci Date: 2009-04-28

2. Antimicrobial properties of green tea catechins.

Authors: Peter W Taylor; Jeremy M T Hamilton-Miller; Paul D Stapleton
Journal: Food Sci Technol Bull Date: 2005

3. Green tea polyphenol, epigallocatechin-3-gallate, possesses the antiviral activity necessary to fight against the hepatitis B virus replication in vitro.

Authors: Jing-yao Pang; Kui-jun Zhao; Jia-bo Wang; Zhi-jie Ma; Xiao-he Xiao
Journal: J Zhejiang Univ Sci B Date: 2014-06 Impact factor: 3.066

Polyphenolic antioxidant (-)-epigallocatechin-3-gallate from green tea as a candidate anti-HIV agent.

1. Tea polyphenols exerts anti-hepatitis B virus effects in a stably HBV-transfected cell line.

2. Antimicrobial properties of green tea catechins.

3. Green tea polyphenol, epigallocatechin-3-gallate, possesses the antiviral activity necessary to fight against the hepatitis B virus replication in vitro.

4. A small molecule inhibits virion attachment to heparan sulfate- or sialic acid-containing glycans.

5. Effect of Sinecatechins on HPV-Activated Cell Growth and Induction of Apoptosis.

Review 6. Anti-infective properties of epigallocatechin-3-gallate (EGCG), a component of green tea.

7. The main green tea polyphenol epigallocatechin-3-gallate counteracts semen-mediated enhancement of HIV infection.

8. Green tea (Camellia sinesis) ameliorates female Schistosoma mansoni-induced changes in the liver of Balb/C mice.

9. Preclinical development of the green tea catechin, epigallocatechin gallate, as an HIV-1 therapy.

10. Effects of brewing conditions on the antioxidant capacity of twenty-four commercial green tea varieties.