| Literature DB >> 11918068 |
Yasuhiro Igarashi1, Takayuki Kajiura, Tamotsu Furumai, Hiroshi Hori, Kazuaki Higashi, Tadayuki Ishiyama, Masakazu Uramoto, Yoshimasa Uehara, Toshikazu Oki.
Abstract
Structures of metabolites produced by blocked mutants of Microbispora rosea subsp. hibaria TP-A0121, hibarimicin-producer, were determined by spectroscopic analysis. HMP-Y6 is the dimer of the west half of hibarimicin B, the aglycon of which is the genuine biosynthetic intermediate. HMP-P1 is the shunt product arising from the release of a methanol molecule from hibarimicinone. HMP-P4, the glycoside of HMP-P1, is glycosylated with two amicetoses and two digitoxoses same as hibarimicin B. HMP-M1, M2, M3 and M4 are shunt products derived from the monomeric undecaketide intermediates.Entities:
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Year: 2002 PMID： 11918068 DOI： 10.7164/antibiotics.55.61
Source DB: PubMed Journal: J Antibiot (Tokyo) ISSN： 0021-8820 Impact factor: 2.649