Literature DB >> 11918060

A novel antibiotic CJ-17,572 from a fungus, Pezicula sp.

Yutaka Sugie1, Koen A Dekker, Taisuke Inagaki, Yoon-Jeong Kim, Tatsuo Sakakibara, Shinichi Sakemi, Akemi Sugiura, Lori Brennan, Joan Duignan, Joyce A Sutcliffe, Yasuhiro Kojima.   

Abstract

A new antibiotic, CJ-17,572 (I) was isolated from the fermentation broth of a fungus Pezicula sp. CL11877. The structure of I was determined to be a new equisetin derivative by spectroscopic analyses. The compound inhibits the growth of multi-drug resistant Staphylococcus aureus and Enterococcusfaecalis with IC50s of 10 and 20 microg/ml, respectively.

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Year:  2002        PMID： 11918060     DOI： 10.7164/antibiotics.55.19

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  2 in total

1.  Isolation and identification of an endophytic fungus Pezicula sp. in Forsythia viridissima and its secondary metabolites.

Authors:  Jiaying Wang; Guoping Wang; Yalei Zhang; Biqiang Zheng; Chulong Zhang; Liwei Wang
Journal:  World J Microbiol Biotechnol       Date:  2014-06-14       Impact factor: 3.312

2.  Isolation of pyrrolocins A-C: cis- and trans-decalin tetramic acid antibiotics from an endophytic fungal-derived pathway.

Authors:  Raquel C Jadulco; Michael Koch; Thomas B Kakule; Eric W Schmidt; Anita Orendt; Haiyin He; Jeffrey E Janso; Guy T Carter; Erica C Larson; Christopher Pond; Teatulohi K Matainaho; Louis R Barrows
Journal:  J Nat Prod       Date:  2014-10-29       Impact factor: 4.050
  2 in total

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