Literature DB >> 11914974

Four highly oxygenated isopimarane-type diterpenes of Orthosiphon stamineus.

Suresh Awale, Yasuhiro Tezuka, Arjun H Banskota, Kyoji Kouda, Kyaw Myint Tun, Shigetoshi Kadota.   

Abstract

Four highly oxygenated isopimarane-type diterpenes, named orthosiphols O, P and Q and nororthosiphonolide A, have been isolated from the aerial parts of Orthosiphon stamineus from Myanmar, together with three known diterpenes, orthosiphols D and E and orthosiphonone A. Their structures were determined on the basis of extensive spectral analysis. All the isolated compounds displayed mild antiproliferative activities against highly liver metastatic colon 26-L5 carcinoma and human HT-1080 fibrosarcoma cell lines.

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Year:  2002        PMID: 11914974     DOI: 10.1055/s-2002-23137

Source DB:  PubMed          Journal:  Planta Med        ISSN: 0032-0943            Impact factor:   3.352


  4 in total

1.  Bioactive Compounds from Medicinal Plants in Myanmar.

Authors:  Nwet Nwet Win; Hiroyuki Morita
Journal:  Prog Chem Org Nat Prod       Date:  2021

2.  Antiapoptotic and Antioxidant Properties of Orthosiphon stamineus Benth (Cat's Whiskers): Intervention in the Bcl-2-Mediated Apoptotic Pathway.

Authors:  Siddig Ibrahim Abdelwahab; Syam Mohan; Manal Mohamed Elhassan; Nabil Al-Mekhlafi; Abdelbasit Adam Mariod; Ahmad Bustamam Abdul; Mahmood Ameen Abdulla; Khalid M Alkharfy
Journal:  Evid Based Complement Alternat Med       Date:  2010-12-30       Impact factor: 2.629

Review 3.  Orthosiphon stamineus Benth. is an Outstanding Food Medicine: Review of Phytochemical and Pharmacological Activities.

Authors:  Kamran Ashraf; Sadia Sultan; Aishah Adam
Journal:  J Pharm Bioallied Sci       Date:  2018 Jul-Sep

4.  HPLC and anti-inflammatory studies of the flavonoid rich chloroform extract fraction of Orthosiphon stamineus leaves.

Authors:  Mun Fei Yam; Vuanghao Lim; Ibrahim Muhammad Salman; Omar Ziad Ameer; Lee Fung Ang; Noersal Rosidah; Muthanna Fawzy Abdulkarim; Ghassan Zuhair Abdullah; Rusliza Basir; Amirin Sadikun; Mohd Zaini Asmawi
Journal:  Molecules       Date:  2010-06-21       Impact factor: 4.411

  4 in total

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