Literature DB >> 11914965

Bisxanthones from Hypericum japonicum: inhibitors of PAF-induced hypotension.

Kyoko Ishiguro1, Satoko Nagata, Hisae Oku, Masae Yamaki.   

Abstract

The CHCl3-soluble part (HJ) of the MeOH extract from Hypericum japonicum afforded new bisxanthones, jacarelhyperols A (1) and B (2). The structures were elucidated by spectral methods. These compounds and HJ showed significant inhibitory effects against PAF-induced hypotension by an in vivo evaluation method, which can reveal the pharmacological action of the test material.

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Year:  2002        PMID: 11914965     DOI: 10.1055/s-2002-23125

Source DB:  PubMed          Journal:  Planta Med        ISSN: 0032-0943            Impact factor:   3.352


  3 in total

1.  The Phytochemistry and Pharmacology of Hypericum.

Authors:  Chuan-Yun Xiao; Qing Mu; Simon Gibbons
Journal:  Prog Chem Org Nat Prod       Date:  2020

2.  Xanthones from the Bark of Garcinia xanthochymus and the Mechanism of Induced Apoptosis in Human Hepatocellular Carcinoma HepG2 Cells via the Mitochondrial Pathway.

Authors:  Shan Jin; Kuan Shi; Liu Liu; Yu Chen; Guangzhong Yang
Journal:  Int J Mol Sci       Date:  2019-09-27       Impact factor: 5.923

3.  Jacarelhyperol A induced apoptosis in leukaemia cancer cell through inhibition the activity of Bcl-2 proteins.

Authors:  Shoude Zhang; Jun Yin; Xia Li; Jigang Zhang; Rongcai Yue; Yanyan Diao; Honglin Li; Hui Wang; Lei Shan; Weidong Zhang
Journal:  BMC Cancer       Date:  2014-09-22       Impact factor: 4.638

  3 in total

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