Literature DB >> 1191441

Quantitation of infarct size in man by means of plasma enzyme levels.

S A Witteveen, H C Hemker, L Hollaar, W T Hermens.   

Abstract

A method is described in which the extent of myocardial infarction in man is assessed by mathematical analysis of the rise in plasma enzyme levels after infarction. Five enzymes are used in this study: lactate dehydrogenase (LDH); alpha-hydroxybutyrate dehydrogenase (alpha-HBDH); aspartate aminotransferase (GOT); creatine phosphokinase (CPK); and phosphohexoseisomerase (PHI). It is shown that a reasonable assessment of the total enzyme release, reflecting the extent of the infarcted area, can be made when a sufficient number of blood samples are taken after infarction. This could provide a method by which to judge therapeutic effects of intervention in the course of a myocardial infarction, as demonstrated in this study by the assessment of the effect of urokinase on the enzyme release after an infarct.

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Year:  1975        PMID： 1191441      PMCID： PMC482877          DOI： 10.1136/hrt.37.8.795

Source DB:  PubMed          Journal:  Br Heart J        ISSN： 0007-0769


  16 in total

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Journal:  Am J Cardiol       Date:  1974-01       Impact factor: 2.778

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Journal:  Schweiz Med Wochenschr       Date:  1973-12-15

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Journal:  J Lab Clin Med       Date:  1967-04

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Journal:  Circulation       Date:  1971-01       Impact factor: 29.690

8.  Quantitative study of infarcted myocardium in cardiogenic shock.

Authors:  C Harnarayan; M A Bennett; B L Pentecost; D B Brewer
Journal:  Br Heart J       Date:  1970-11

9.  Coronary artery reperfusion. II. Reduction of myocardial infarct size at 1 week after the coronary occlusion.

Authors:  W R Ginks; H D Sybers; P R Maroko; J W Covell; B E Sobel; J Ross
Journal:  J Clin Invest       Date:  1972-10       Impact factor: 14.808

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Authors:  W E Shell; J F Lavelle; J W Covell; B E Sobel
Journal:  J Clin Invest       Date:  1973-10       Impact factor: 14.808
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  14 in total

1.  Recognition and quantification of myocardial injury by means of plasma enzyme and isoenzyme activities after cardiac surgery.

Authors:  A van der Laarse; H A Davids; L Hollaar; E J van der Valk; S A Witteveen; W T Hermens
Journal:  Br Heart J       Date:  1979-06

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Authors:  C de Zwaan; G M Willems; F Vermeer; J Res; F W Verheugt; A van der Laarse; M L Simoons; J Lubsen; W T Hermens
Journal:  Br Heart J       Date:  1988-02

3.  Extent of myocardial damage after open-heart surgery assessed from serial plasma enzyme levels in either of two periods (1975 and 1980).

Authors:  H A Davids; W T Hermens; L Hollaar; A van der Laarse; H A Huysmans
Journal:  Br Heart J       Date:  1982-02

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Authors:  J Aznar; M T Santos; J Valles; J Sala
Journal:  J Clin Pathol       Date:  1983-06       Impact factor: 3.411

5.  Evaluation of evolution of myocardial infarction by serial determinations of serum creatine kinase activity.

Authors:  M Inoue; M Hori; S Fukui; H Abe; T Minamino
Journal:  Br Heart J       Date:  1977-05

6.  Investigation of effects of Lacidipine, Ramipril and Valsartan on DNA damage and oxidative stress occurred in acute and chronic periods following isoproterenol-induced myocardial infarct in rats.

Authors:  Mevlut Sait Keles; Yasin Bayir; Halis Suleyman; Zekai Halici
Journal:  Mol Cell Biochem       Date:  2009-03-19       Impact factor: 3.396

7.  Nitrates in myocardial infarction: influence on infarct size, reperfusion, and ventricular remodelling.

Authors:  J L Morris; A G Zaman; J H Smyllie; J C Cowan
Journal:  Br Heart J       Date:  1995-04

8.  Advantages of technetium pyrophosphate scintigraphy over plasma enzyme analysis in estimation of anterior myocardial infarct size.

Authors:  S Saltissi; P S Robinson; M M Webb-Peploe; D J Coltart; D N Croft
Journal:  Br Heart J       Date:  1981-02

9.  Chest pain in the early recognition of large infarcts.

Authors:  J R Ledwich
Journal:  Can Med Assoc J       Date:  1977-01-08       Impact factor: 8.262

10.  Biochemical effects of Solidago virgaurea extract on experimental cardiotoxicity.

Authors:  Walid Hamdy El-Tantawy
Journal:  J Physiol Biochem       Date:  2013-07-20       Impact factor: 4.158
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