BACKGROUND: Helicobacter pylori (H. pylori) has been etiologically linked with primary gastric lymphoma (PGL) and gastric carcinoma (GC). There are a few reports of occurrence of both diseases in the same patients with H. pylori infection. CASE PRESENTATION: We report a patient with PGL in whom the tumor regressed after surgical resection combined with eradication of H. pylori infection. However, he developed GC on follow up; this was temporally associated with recrudescence/re-infection of H. pylori. This is perhaps first report of such occurrence. CONCLUSIONS: Possible cause and effect relationship between H. pylori infection and both PGL and GC is discussed. This case also documents a unique problem in management of PGL in tropical countries where re-infection with H. pylori is supposed to be high.
BACKGROUND:Helicobacter pylori (H. pylori) has been etiologically linked with primary gastric lymphoma (PGL) and gastric carcinoma (GC). There are a few reports of occurrence of both diseases in the same patients with H. pyloriinfection. CASE PRESENTATION: We report a patient with PGL in whom the tumor regressed after surgical resection combined with eradication of H. pyloriinfection. However, he developed GC on follow up; this was temporally associated with recrudescence/re-infection of H. pylori. This is perhaps first report of such occurrence. CONCLUSIONS: Possible cause and effect relationship between H. pyloriinfection and both PGL and GC is discussed. This case also documents a unique problem in management of PGL in tropical countries where re-infection with H. pylori is supposed to be high.
Authors: N Hasegawa; K Kato; K Yamada; K Morita; M Kuroiwa; H Ito; T Kamioka; T Matsuura; A Taguchi; K Ono; Y Suzuki; H Goto Journal: Gastrointest Endosc Date: 2001-04 Impact factor: 9.427
Authors: A Morgner; S Miehlke; M Stolte; A Neubauer; B Alpen; C Thiede; H Klann; F X Hierlmeier; C Ell; G Ehninger; E Bayerdörffer Journal: World J Gastroenterol Date: 2001-04 Impact factor: 5.742