Literature DB >> 11914021

Are the insulin-like growth factors relevant to cancer?

D Yee1.   

Abstract

Recognition of molecular pathways relevant to cancer biology have led to advances in prevention and treatment. Numerous laboratory and clinical investigations have implicated the insulin-like growth factors (IGFs) in tumourigenesis. In this review, the evidence for the involvement of IGFs in cancer is discussed. While these data are persuasive, it is clear that additional methods to regulate IGF action in cancer patients are needed to substantiate the role of this growth factor family in cancer biology. Copyright 2001 Elsevier Science Ltd.

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Year:  2001        PMID： 11914021     DOI： 10.1054/ghir.2001.0256

Source DB:  PubMed          Journal:  Growth Horm IGF Res        ISSN： 1096-6374            Impact factor:   2.372


  4 in total

1.  No evidence of increased risk of malignancies in patients with diabetes treated with insulin detemir: a meta-analysis.

Authors:  A Dejgaard; H Lynggaard; J Råstam; M Krogsgaard Thomsen
Journal:  Diabetologia       Date:  2009-10-17       Impact factor: 10.122

2.  C/EBPbeta regulates body composition, energy balance-related hormones and tumor growth.

Authors:  Jennifer Staiger; Mary J Lueben; David Berrigan; Radek Malik; Susan N Perkins; Stephen D Hursting; Peter F Johnson
Journal:  Carcinogenesis       Date:  2008-12-04       Impact factor: 4.944

3.  Evaluation of the synergistic effect of insulin resistance and insulin-like growth factors on the risk of breast carcinoma.

Authors:  Alecia Malin; Qi Dai; Herbert Yu; Xiao-Ou Shu; Fan Jin; Yu-Tang Gao; Wei Zheng
Journal:  Cancer       Date:  2004-02-15       Impact factor: 6.860

4.  Critical prosurvival roles for C/EBP beta and insulin-like growth factor I in macrophage tumor cells.

Authors:  Jennifer Wessells; Shoshana Yakar; Peter F Johnson
Journal:  Mol Cell Biol       Date:  2004-04       Impact factor: 4.272
  4 in total

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