| Literature DB >> 11913986 |
Abstract
In 1951, the young hematologist in training, Dr. William Harrington, infused himself with plasma from a patient with immune thrombocytopenic purpura (ITP). He rapidly developed severe, but transient, thrombocytopenia and was at risk for serious hemorrhage. Thus, the humoral autoimmune cause of ITP was established. Since 1953, when Dr. Harrington's in vivo studies ended, in vitro investigations have aimed to determine the molecular and cellular details of immune-mediated platelet destruction. Copyright 2002, Elsevier Science Ltd. All rights reserved.Entities:
Mesh：
Year: 2002 PMID： 11913986 DOI： 10.1054/blre.2001.0173
Source DB: PubMed Journal: Blood Rev ISSN： 0268-960X Impact factor: 8.250