PURPOSE: To describe clinical and pathological features of Hydroview intraocular lenses undergoing delayed surface opacification resulting in visual deterioration. METHODS: Twenty one eyes which underwent uncomplicated phacoemulsification and Hydroview lens implantation with good visual recovery, presenting at 46-146 weeks post-surgery with visual deterioration and glare symptoms resulting from opacification of the implants, were included in the study. Twelve eyes had severe opacification, of which nine underwent intraocular lens exchange and three more are still awaiting surgery. The method of explantation is described. The explanted intraocular lenses were examined using light microscopy, scanning electron microscopy and x-ray microanalysis using a light element detector. RESULTS: Light microscopy and scanning electron microscopy revealed diffuse granular deposits of approximately 5 microm diameter covering the optic surfaces but sparing the lens haptics. Light microscopic staining techniques and x-ray microanalysis confirm the major component of the deposits to be calcium phosphate salts. CONCLUSIONS: Late opacification of Hydroview intraocular lens implants is uncommon and aetiology seems to be multifactorial. Implant exchange is necessary to restore sight in some cases. As new materials are increasingly used it is important to highlight such unusual occurrences.
PURPOSE: To describe clinical and pathological features of Hydroview intraocular lenses undergoing delayed surface opacification resulting in visual deterioration. METHODS: Twenty one eyes which underwent uncomplicated phacoemulsification and Hydroview lens implantation with good visual recovery, presenting at 46-146 weeks post-surgery with visual deterioration and glare symptoms resulting from opacification of the implants, were included in the study. Twelve eyes had severe opacification, of which nine underwent intraocular lens exchange and three more are still awaiting surgery. The method of explantation is described. The explanted intraocular lenses were examined using light microscopy, scanning electron microscopy and x-ray microanalysis using a light element detector. RESULTS: Light microscopy and scanning electron microscopy revealed diffuse granular deposits of approximately 5 microm diameter covering the optic surfaces but sparing the lens haptics. Light microscopic staining techniques and x-ray microanalysis confirm the major component of the deposits to be calcium phosphate salts. CONCLUSIONS: Late opacification of Hydroview intraocular lens implants is uncommon and aetiology seems to be multifactorial. Implant exchange is necessary to restore sight in some cases. As new materials are increasingly used it is important to highlight such unusual occurrences.
Authors: R W Altaie; T Costigan; S Donegan; P O'brien; U Mahmood; A J Bogdan; S Beatty Journal: Graefes Arch Clin Exp Ophthalmol Date: 2005-06-11 Impact factor: 3.117
Authors: Nathaniel E Knox Cartwright; Eric J Mayer; Brendan M McDonald; Andrew Skinner; Chris J Salter; Derek M Tole; John M Sparrow; Andrew D Dick; David J P Ferguson Journal: Br J Ophthalmol Date: 2006-09-20 Impact factor: 4.638