Literature DB >> 11913536

Mass spectrometric separation and determination of N1,N12-diacetylspermine in the urine of cancer patients.

Masaki Kobayashi1, Keijiro Samejima, Kyoko Hiramatsu, Masao Kawakita.   

Abstract

An ionspray ionization mass-spectrometric method for the determination of N1,N12-diacetylspermine (Ac2Spm) was developed using 15N-labeled Ac2Spm as the internal standard. Concentrations of Ac2Spm in the urine obtained from 17 cancer patients measured by the present method correlated well with those measured by ELISA, showing the usefulness of the two methods.

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Year:  2002        PMID: 11913536     DOI: 10.1248/bpb.25.372

Source DB:  PubMed          Journal:  Biol Pharm Bull        ISSN: 0918-6158            Impact factor:   2.233


  1 in total

1.  Increase of N1, N12-diacetylspermine in tissues from colorectal cancer and its liver metastasis.

Authors:  Go Kuwata; Kyoko Hiramatsu; Keijiro Samejima; Kaori Iwasaki; Kei-ichi Takahashi; Koichi Koizumi; Shin-ichiro Horiguchi; Shun-suke Moriya; Masaki Kobayashi; Masao Kawakita
Journal:  J Cancer Res Clin Oncol       Date:  2013-02-27       Impact factor: 4.553

  1 in total

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