Literature DB >> 11913072

Ethics of clinical research in the developing world.

Jack Killen1, Christine Grady, Gregory K Folkers, Anthony S Fauci.   

Abstract

Many commentators believe that all clinical-trial participants must receive a level of care equivalent to the world's best. Using HIV/AIDS research as an example, we show how this 'Uniform Care Requirement' can undermine biomedical research aimed at improving global health, and then we point towards a more rational and balanced approach to ethical assessment.

Entities:  

Keywords:  Biomedical and Behavioral Research

Mesh：

Year:  2002        PMID： 11913072     DOI： 10.1038/nri745

Source DB:  PubMed          Journal:  Nat Rev Immunol        ISSN： 1474-1733            Impact factor:   53.106


  6 in total

1.  The impact of genomics on global health.

Authors:  Tikki Pang
Journal:  Am J Public Health       Date:  2002-07       Impact factor: 9.308

2.  The standard of care debate: can research in developing countries be both ethical and responsive to those countries' health needs?

Authors:  David Wendler; Ezekiel J Emanuel; Reidar K Lie
Journal:  Am J Public Health       Date:  2004-06       Impact factor: 9.308

3.  Equitable treatment for HIV/AIDS clinical trial participants: a focus group study of patients, clinician researchers, and administrators in Western Kenya.

Authors:  D N Shaffer; V N Yebei; J B Ballidawa; J E Sidle; J Y Greene; E M Meslin; S J N Kimaiyo; W M Tierney
Journal:  J Med Ethics       Date:  2006-01       Impact factor: 2.903

4.  Human rights, cultural pluralism, and international health research.

Authors:  Patricia A Marshall
Journal:  Theor Med Bioeth       Date:  2005

5.  Ethics of healthcare research in developing countries.

Authors:  Alimuddin Zumla; Anthony Costello
Journal:  J R Soc Med       Date:  2002-06       Impact factor: 18.000

6.  International Clinical Trials in Latin American and Caribbean Countries: Research and Development to Meet Local Health Needs.

Authors:  Ricardo E da Silva; Angélica A Amato; Dirce B Guilhem; Marta R de Carvalho; Maria R C G Novaes
Journal:  Front Pharmacol       Date:  2018-01-05       Impact factor: 5.810
  6 in total

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