Literature DB >> 11912391

The patient with chronic epididymitis: characterization of an enigmatic syndrome.

J Curtis Nickel1, D Robert Siemens, Kyle R Nickel, Joe Downey.   

Abstract

PURPOSE: We provide a baseline description of men diagnosed with chronic epididymitis, explore relevant associations that may be important etiological factors and suggest a classification system and specific symptom assessment tool.
MATERIALS AND METHODS: Men diagnosed with chronic epididymitis, described as symptoms of discomfort or pain at least 3 months in duration in the scrotum, testicle or epididymis localized to 1 or each epididymis on clinical examination, completed an extensive specific clinical inventory questionnaire. Evaluation included demographics, preceding and concurrent clinical history, duration since diagnosis, associated and previous clinical associations, frequency and severity of prostatitis, voiding and sexual symptoms, specific and general quality of life, and history of investigation and/or treatment for the condition. Volunteers with no past or concurrent history of chronic epididymitis completed similar clinical inventory questionnaires.
RESULTS: A total of 50 consecutive men 21 to 83 years old (average age 46) diagnosed with chronic epididymitis who had an average symptom duration of 4.9 years (range 0.25 to 29) were enrolled in the study. The average pain score plus or minus standard deviation was 4.7 +/- 2.1 (range 0 to 10). Of the men 16% were reasonably satisfied with their quality of life. Although 66% of the patients thought about the symptoms some or a lot, in only 30% did symptoms keep them from doing the kinds of things that they would usually do. The most common previous therapies recollected by the patients were antibiotics (74%) and anti-inflammatory agents (36%). At the time of the survey 26% of the men were on some type of pain medication. There were no significant epidemiological, sexual, medical or associated factors that differentiated patients with chronic epididymitis from the 20 controls. A chronic epididymitis classification system (inflammatory, obstructive and epididymalgia) and a symptom assessment index based on assessing pain and quality of life-impact was developed.
CONCLUSIONS: This comprehensive clinical survey of men diagnosed with chronic epididymitis is the first step for defining and characterizing this particular population. Development of a classification system and symptom assessment index may direct further studies in the etiology, epidemiology and management of chronic epididymitis.

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Mesh:

Year:  2002        PMID: 11912391

Source DB:  PubMed          Journal:  J Urol        ISSN: 0022-5347            Impact factor:   7.450


  17 in total

Review 1.  Chronic Scrotal Pain.

Authors:  Christopher Wu; Keith Jarvi
Journal:  Curr Urol Rep       Date:  2018-05-31       Impact factor: 3.092

Review 2.  Chronic prostatitis/chronic pelvic pain syndrome and interstitial cystitis: are they related?

Authors:  Michel A Pontari
Journal:  Curr Urol Rep       Date:  2006-07       Impact factor: 3.092

3.  Canadian Urological Association best practice report on chronic scrotal pain.

Authors:  Keith A Jarvi; Christopher Wu; J Curtis Nickel; Trustin Domes; John Grantmyre; Armand Zini
Journal:  Can Urol Assoc J       Date:  2018-02-23       Impact factor: 1.862

Review 4.  Orchialgia and the chronic pelvic pain syndrome.

Authors:  Parviz K Kavoussi; Raymond A Costabile
Journal:  World J Urol       Date:  2013-05-05       Impact factor: 4.226

5.  Frequency and severity of chronic scrotal pain in Canadian men presenting to urologists for infertility investigations.

Authors:  Aosama Aljumaily; Ellen Forbes; Hind Abdul Jaleel Al-Khazraji; Allan Gordon; Susan Lau; Keith Allen Jarvi
Journal:  Transl Androl Urol       Date:  2017-12

6.  Characteristics and Etiologies of Chronic Scrotal Pain: A Common but Poorly Understood Condition.

Authors:  Aosama Aljumaily; Hind Al-Khazraji; Allan Gordon; Susan Lau; Keith A Jarvi
Journal:  Pain Res Manag       Date:  2017-03-02       Impact factor: 3.037

Review 7.  Current trends and therapies in orchialgia management.

Authors:  Kevin Campbell; Larry Lipshultz
Journal:  Ther Adv Urol       Date:  2021-06-22

Review 8.  Microsurgical denervation of the rat spermatic cord and its connection to the diagnosis and treatment of chronic orchialgia: a bench to bedside experience.

Authors:  Asha E Jamzadeh; Melissa A Laudano; E Charles Osterberg; Marc Goldstein; Philip S Li
Journal:  Transl Androl Urol       Date:  2014-03

Review 9.  Chronic orchialgia: Review of treatments old and new.

Authors:  Bayo Tojuola; Jeffrey Layman; Ibrahim Kartal; Ahmet Gudelogul; Jamin Brahmbhatt; Sijo Parekattil
Journal:  Indian J Urol       Date:  2016 Jan-Mar

10.  Chronic scrotal pain may lead to reduced sexual function and interest, while sexual activity may worsen chronic scrotal pain: "double jeopardy".

Authors:  Aosama Aljumaily; Hind Abdul Jaleel Al-Khazraji; Allan Gordon; Susan Lau; Keith Allen Jarvi
Journal:  Transl Androl Urol       Date:  2018-03
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