BACKGROUND & AIMS: Hepatopulmonary syndrome (HPS) has been predominantly detected in cirrhotic patients and rarely in patients with noncirrhotic portal hypertension. The aim of this study was to determine the occurrence of HPS in patients with Budd-Chiari syndrome (only anecdotal reports available) and evaluate the role of venous decompression in its reversal. METHODS: Twenty-nine consecutive cases of Budd-Chiari syndrome without primary cardiopulmonary disease were investigated by air contrast echocardiography and arterial blood gas analysis. Venous decompression (e.g., by balloon cavoplasty) was attempted when feasible. RESULTS: Eight cases (27.6%) of HPS and 9 cases (31.0%) with positive contrast echocardiography but unimpaired oxygenation were detected. Duration of disease was longer (P = 0.026) among those with positive contrast echocardiography. Cavoplasty reversed 4 of 5 cases of HPS and 2 of 2 cases with positive contrast echocardiography alone. Venous decompression by drainage of amebic liver abscess (which was compressing hepatic venous outflow) also reversed 1 case of HPS. HPS was relieved by venous decompression in 5 of 6 cases. CONCLUSIONS: HPS developed in a substantial fraction of our patients with Budd-Chiari syndrome, with positive contrast echocardiography occurring mainly in the benign, slowly progressing variety. Venous decompression showed promise in reversing such cases.
BACKGROUND & AIMS:Hepatopulmonary syndrome (HPS) has been predominantly detected in cirrhotic patients and rarely in patients with noncirrhotic portal hypertension. The aim of this study was to determine the occurrence of HPS in patients with Budd-Chiari syndrome (only anecdotal reports available) and evaluate the role of venous decompression in its reversal. METHODS: Twenty-nine consecutive cases of Budd-Chiari syndrome without primary cardiopulmonary disease were investigated by air contrast echocardiography and arterial blood gas analysis. Venous decompression (e.g., by balloon cavoplasty) was attempted when feasible. RESULTS: Eight cases (27.6%) of HPS and 9 cases (31.0%) with positive contrast echocardiography but unimpaired oxygenation were detected. Duration of disease was longer (P = 0.026) among those with positive contrast echocardiography. Cavoplasty reversed 4 of 5 cases of HPS and 2 of 2 cases with positive contrast echocardiography alone. Venous decompression by drainage of amebic liver abscess (which was compressing hepatic venous outflow) also reversed 1 case of HPS. HPS was relieved by venous decompression in 5 of 6 cases. CONCLUSIONS: HPS developed in a substantial fraction of our patients with Budd-Chiari syndrome, with positive contrast echocardiography occurring mainly in the benign, slowly progressing variety. Venous decompression showed promise in reversing such cases.
Authors: Beverley Newman; Jeffrey A Feinstein; Ronald A Cohen; Brian Feingold; Jacqueline Kreutzer; Hitendra Patel; Fandics P Chan Journal: Pediatr Radiol Date: 2010-01-13
Authors: Binay K De; Deep Dutta; Subrata K Pal; Subhabrata Gangopadhyay; Sumanta Das Baksi; Adyapad Pani Journal: Can J Gastroenterol Date: 2010-03 Impact factor: 3.522
Authors: Graciela Martinez-Palli; Britt B Drake; Joan-Carles Garcia-Pagan; Joan-Albert Barbera; Miguel R Arguedas; Robert Rodriguez-Roisin; Jaume Bosch; Michael B Fallon Journal: World J Gastroenterol Date: 2005-11-21 Impact factor: 5.742
Authors: Nikolaos Tzovaras; Aggelos Stefos; Sarah P Georgiadou; Nikolaos Gatselis; Georgia Papadamou; Eirini Rigopoulou; Maria Ioannou; Ioannis Skoularigis; Georgios N Dalekos Journal: World J Gastroenterol Date: 2006-01-14 Impact factor: 5.742