Literature DB >> 11910198

Identification of anticoagulant activities in salivary gland extracts of four horsefly species (Diptera, tabanidae).

M Kazimírová1, M Sulanová, M Kozánek, P Takác, M Labuda, P A Nuttall.   

Abstract

Anticoagulant activities against the extrinsic and intrinsic coagulation pathways were identified in salivary gland extracts (SGE) prepared from four tabanids (Hybomitra muehlfeldi, Tabanus autumnalis, Haematopota pluvialis, Heptatoma pellucens). All extracts prolonged human plasma clotting time in a dose-dependent manner and inhibited thrombin activity in the chromogenic substrate assay. Horsefly SGE did not inhibit factor Xa. Partial purification of SGE proteins using reversed-phase high-performance liquid chromatography revealed species-specific differences in the elution profiles and range of fractions with anticoagulant activities. Copyright 2002 S. Karger AG, Basel

Entities:  

Mesh：

Substances：

Year:  2001        PMID： 11910198     DOI： 10.1159/000048076

Source DB:  PubMed          Journal:  Haemostasis        ISSN： 0301-0147


  7 in total

1.  Anti-thrombosis repertoire of blood-feeding horsefly salivary glands.

Authors:  Dongying Ma; Yipeng Wang; Hailong Yang; Jing Wu; Shu An; Li Gao; Xueqing Xu; Ren Lai
Journal:  Mol Cell Proteomics       Date:  2009-06-16       Impact factor: 5.911

2.  Anticoagulation activity of salivary gland extract of oriental blackfly Simulium indicum.

Authors:  Subhalaxmi Borah; Ashok Naglot; Sewali Goswami; Imtiaz Rahman; Manab Deka
Journal:  Asian Pac J Trop Biomed       Date:  2014-05

3.  An insight into the sialome of the horse fly, Tabanus bromius.

Authors:  José M C Ribeiro; Maria Kazimirova; Peter Takac; John F Andersen; Ivo M B Francischetti
Journal:  Insect Biochem Mol Biol       Date:  2015-09-11       Impact factor: 4.714

4.  Effect of saliva from horse fly Hybomitra bimaculata on kinetic properties of Na,K-ATPase: possible role in regulation of relaxation.

Authors:  Katarína Wachalová; Jana Vlkovicová; Veronika Javorková; Lucia Mézešová; Peter Takác; Milan Kozánek; Milan Labuda; Patricia A Nuttall; Norbert Vrbjar
Journal:  Interdiscip Toxicol       Date:  2011-09

5.  A confirmed feeding attempt by the haematophagous horse fly Philoliche (Philoliche) rondani (Bertoloni, 1861) (Diptera: Tabanidae) on fresh carrion.

Authors:  Benjamin Miller; Martin Villet; John Mark Midgley
Journal:  Biodivers Data J       Date:  2022-03-31

6.  A potent anti-inflammatory peptide from the salivary glands of horsefly.

Authors:  Lin Wei; Chunjing Huang; Hailong Yang; Min Li; Juanjuan Yang; Xue Qiao; Lixian Mu; Fei Xiong; Jing Wu; Wei Xu
Journal:  Parasit Vectors       Date:  2015-10-24       Impact factor: 3.876

7.  Acute bullous hemorrhagic prurigo: a diagnostic challenge.

Authors:  Vidal Haddad; Cecília Guimarães Ferreira Fonseca; Adriana Lúcia Mendes
Journal:  An Bras Dermatol       Date:  2020-09-18       Impact factor: 1.896
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.