| Literature DB >> 11909746 |
Samuel Wyllie1, Philip Seu, John A Goss.
Abstract
Slc11a1 (solute carrier family 11 member 1) (formerly Nramp1) modulation of iron metabolism in macrophages plays an important role in early phase macrophage activation, and therefore host innate immunity. This review focuses on the role of Nramp1 in intramacrophage iron metabolism, with emphasis on the two prevailing mechanisms of Nramp1 modulation of iron metabolism in macrophages.Entities:
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Year: 2002 PMID: 11909746 DOI: 10.1016/s1286-4579(02)01548-4
Source DB: PubMed Journal: Microbes Infect ISSN: 1286-4579 Impact factor: 2.700