Literature DB >> 11909713

Thalidomide and its analogues as cyclooxygenase inhibitors.

Tomomi Noguchi1, Rumiko Shimazawa, Kazuo Nagasawa, Yuichi Hashimoto.   

Abstract

Thalidomide showed cyclooxygenase (COX)-1/2 inhibitory activity with a potency comparable to that of aspirin. Structural development studies of thalidomide resulted in potent COX-1/2 inhibitors, and COX-1-selective and COX-2-selective inhibitors.

Entities:  

Mesh：

Substances：

Year:  2002        PMID： 11909713     DOI： 10.1016/s0960-894x(02)00084-7

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  6 in total

1.  Free energy perturbation approach to the critical assessment of selective cyclooxygenase-2 inhibitors.

Authors:  Hwangseo Park; Sangyoub Lee
Journal:  J Comput Aided Mol Des       Date:  2005-01       Impact factor: 3.686

2.  In vitro anticancer property of a novel thalidomide analogue through inhibition of NF-kappaB activation in HL-60 cells.

Authors:  Min Li; Wan Sun; Ya-ping Yang; Bo Xu; Wen-yuan Yi; Yan-xia Ma; Zhong-jun Li; Jing-rong Cui
Journal:  Acta Pharmacol Sin       Date:  2008-12-22       Impact factor: 6.150

Review 3.  The NF-kappaB/IL-6 pathway in metastatic androgen-independent prostate cancer: new therapeutic approaches?

Authors:  Bernard Paule; Stéphane Terry; Laurence Kheuang; Pascale Soyeux; Francis Vacherot; Alexandre de la Taille
Journal:  World J Urol       Date:  2007-05-31       Impact factor: 4.226

4.  Polyunsaturated fatty acids synergize with lipid droplet binding thalidomide analogs to induce oxidative stress in cancer cells.

Authors:  László G Puskás; Liliána Z Fehér; Csaba Vizler; Ferhan Ayaydin; Erzsébet Rásó; Eszter Molnár; István Magyary; Iván Kanizsai; Márió Gyuris; Ramóna Madácsi; Gabriella Fábián; Klaudia Farkas; Péter Hegyi; Ferenc Baska; Béla Ozsvári; Klára Kitajka
Journal:  Lipids Health Dis       Date:  2010-06-02       Impact factor: 3.876

5.  Therapeutic Effects of a Novel Phenylphthalimide Analog for Corneal Neovascularization and Retinal Vascular Leakage.

Authors:  Bing Wang; Pui-Kai Li; Jian-Xing Ma; Danyang Chen
Journal:  Invest Ophthalmol Vis Sci       Date:  2018-07-02       Impact factor: 4.799

6.  Structure-Based Screening to Discover New Inhibitors for Papain-like Proteinase of SARS-CoV-2: An In Silico Study.

Authors:  Mostafa Jamalan; Ebrahim Barzegari; Fathollah Gholami-Borujeni
Journal:  J Proteome Res       Date:  2020-12-22       Impact factor: 4.466
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.