| Literature DB >> 11909711 |
Felikss Mutulis1, Ilze Mutule, Maris Lapins, Jarl E S Wikberg.
Abstract
Presumed pharmacophoric groups of melanocortin peptides (naphthalene, amino or guanidine, and indole moieties) were combined in mimetics molecules looking for their favorable location for activity at melanocortin (MC) receptors. Twenty-two compounds were prepared and tested. The best of these displayed micromolar affinities for the MC receptors.Entities:
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Year: 2002 PMID： 11909711 DOI： 10.1016/s0960-894x(02)00088-4
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823