| Literature DB >> 11909701 |
Ao Zhang1, Guochun Zhou, Suo-Bao Rong, Kenneth M Johnson, Mei Zhang, Alan P Kozikowski.
Abstract
A series of (1S,3S,6R,10S)-(Z)-9-(thienylmethylene- or substituted thienylmethylene)-7-azatricyclo[4.3.1.0(3,7)]decanes was prepared and evaluated for the ability to block dopamine, serotonin, and norepinephrine reuptake by their respective transporters. Compound 5b is a NET-selective inhibitor, 5c is a mixed NET- and SERT-selective inhibitor, while 11 is a SERT-selective inhibitor.Entities:
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Year: 2002 PMID： 11909701 DOI： 10.1016/s0960-894x(02)00103-8
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823