| Literature DB >> 11907329 |
Jean-Pierre Vartanian1, Michel Henry1, Simon Wain-Hobson1.
Abstract
Two full-length human immunodeficiency virus type 1 O sequences are described, one of which was hypermutated in all regions of the genome. This indicates that the intracellular [dTTP]/[dCTP] bias conducive to G-->A hypermutation may be sustained throughout the synthesis of minus-strand DNA. In turn, this suggests the possibility of mutation of host sequences.Entities:
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Year: 2002 PMID: 11907329 DOI: 10.1099/0022-1317-83-4-801
Source DB: PubMed Journal: J Gen Virol ISSN: 0022-1317 Impact factor: 3.891