Literature DB >> 11903626

Structure and evolution of the mitochondrial DNA complete control region in the Drosophila subobscura subgroup.

A Brehm1, D J Harris, M Hernández, V M Cabrera, J M Larruga, F M Pinto, A M González.   

Abstract

The complete A + T-rich region of mitochondrial DNA (mtDNA) has been cloned and sequenced in the species of the Drosophila subobscura subgroup D. subobscura, D. madeirensis and D. guanche. Comparative analysis of these sequences with others already published has identified new sequence motifs that are conserved in Drosophila and other insects. A putative bi-directional promoter and a stop signal are proposed to be involved in the primary mtDNA strand replication of Drosophila. This region strongly resolves relationships of the species included in a phylogenetic analysis, both for closely related species and also at deeper phylogenetic levels when only the left and central domains are taken into account.

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Year:  2001        PMID: 11903626     DOI: 10.1046/j.0962-1075.2001.00295.x

Source DB:  PubMed          Journal:  Insect Mol Biol        ISSN: 0962-1075            Impact factor:   3.585


  10 in total

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  10 in total

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