Literature DB >> 11902569

'Best supportive care' has had its day.

M Cullen1.   

Abstract

The term 'best supportive care' has been used since 1988 to describe the control arm in trials evaluating chemotherapy in advanced cancers. There are problems with this term. First, it implies that we more strenuously optimise these components of care in trials than in routine oncology practise, when there is no evidence that we do. Secondly, the name implies that it is effective, when usually it is not. Finally, 'best' suggests that we have reached a clear landmark of progress in non-chemotherapeutic palliation, when clearly we have not. 'Best supportive care' is an unhelpful and misleading term which should be avoided. In future trials, it should be replaced by 'standard palliative care ' with the type and frequency of key palliative interventions documented.

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Year:  2001        PMID: 11902569     DOI: 10.1016/S1470-2045(00)00260-6

Source DB:  PubMed          Journal:  Lancet Oncol        ISSN: 1470-2045            Impact factor:   41.316


  7 in total

Review 1.  How is best supportive care provided in clinical trials for patients with advanced cancer? A review of registered protocols of clinical trials.

Authors:  Á Sanz Rubiales; M E Sánchez-Gutiérrez; L A Flores Pérez; M L Del Valle Rivero
Journal:  Curr Oncol       Date:  2020-05-01       Impact factor: 3.677

2.  The lack of standard definitions in the supportive and palliative oncology literature.

Authors:  David Hui; Masanori Mori; Henrique A Parsons; Sun Hyun Kim; Zhijun Li; Shamsha Damani; Eduardo Bruera
Journal:  J Pain Symptom Manage       Date:  2011-11-21       Impact factor: 3.612

Review 3.  Concepts and definitions for "supportive care," "best supportive care," "palliative care," and "hospice care" in the published literature, dictionaries, and textbooks.

Authors:  David Hui; Maxine De La Cruz; Masanori Mori; Henrique A Parsons; Jung Hye Kwon; Isabel Torres-Vigil; Sun Hyun Kim; Rony Dev; Ronald Hutchins; Christiana Liem; Duck-Hee Kang; Eduardo Bruera
Journal:  Support Care Cancer       Date:  2012-08-31       Impact factor: 3.603

Review 4.  Lung cancer. 4: chemotherapy for non-small cell lung cancer: the end of the beginning.

Authors:  M Cullen
Journal:  Thorax       Date:  2003-04       Impact factor: 9.139

Review 5.  Supportive care for patients with gastrointestinal cancer.

Authors:  N Ahmed; S Ahmedzai; V Vora; S Hillam; S Paz
Journal:  Cochrane Database Syst Rev       Date:  2004

Review 6.  Best supportive care in clinical trials: review of the inconsistency in control arm design.

Authors:  R D Nipp; D C Currow; N I Cherny; F Strasser; A P Abernethy; S Y Zafar
Journal:  Br J Cancer       Date:  2015-06-11       Impact factor: 7.640

7.  Aerobic physical exercise for adult patients with haematological malignancies.

Authors:  Linus Knips; Nils Bergenthal; Fiona Streckmann; Ina Monsef; Thomas Elter; Nicole Skoetz
Journal:  Cochrane Database Syst Rev       Date:  2019-01-31
  7 in total

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