Literature DB >> 11901593

Treatment of canine atopic dermatitis with zafirlukast, a leukotriene-receptor antagonist: a single-blinded, placebo-controlled study.

David A Senter1, Danny W Scott, William H Miller.   

Abstract

Zafirlukast and placebo were administered orally as individual agents to 20 dogs with atopic dermatitis. The pruritus was effectively reduced by at least 50% in 2/18 (11%) dogs that completed the trial with zafirlukast. Two dogs vomited after administration of the active drug.

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Year:  2002        PMID： 11901593      PMCID： PMC339203     

Source DB:  PubMed          Journal:  Can Vet J        ISSN： 0008-5286            Impact factor:   1.008


  17 in total

1.  Treatment of atopic dermatitis with zafirlukast.

Authors:  E J Zabawski; M A Kahn; L J Gregg
Journal:  Dermatol Online J       Date:  1999-11

Review 2.  Leukotrienes and other products of the 5-lipoxygenase pathway. Biochemistry and relation to pathobiology in human diseases.

Authors:  R A Lewis; K F Austen; R J Soberman
Journal:  N Engl J Med       Date:  1990-09-06       Impact factor: 91.245

3.  Sulphido-leukotriene production from peripheral leukocytes and skin in clinically normal dogs and house dust mite positive atopic dogs.

Authors:  R Marsella; C F Nicklin
Journal:  Vet Dermatol       Date:  2001-02       Impact factor: 1.589

4.  Chemical mediators in atopic dermatitis: involvement of leukotriene B4 released by a type I allergic reaction in the pathogenesis of atopic dermatitis.

Authors:  O Koro; K Furutani; M Hide; S Yamada; S Yamamoto
Journal:  J Allergy Clin Immunol       Date:  1999-04       Impact factor: 10.793

5.  Double-blinded, placebo-controlled, cross-over pilot study on the efficacy of zileuton for canine atopic dermatitis.

Authors:  D W Crow; R Marsella; C F Nicklin
Journal:  Vet Dermatol       Date:  2001-08       Impact factor: 1.589

6.  The leukotriene antagonist montelukast as a therapeutic agent for atopic dermatitis.

Authors:  D J Yanase; K David-Bajar
Journal:  J Am Acad Dermatol       Date:  2001-01       Impact factor: 11.527

7.  Antihistamines in the management of allergic pruritus in dogs and cats.

Authors:  D W Scott; W H Miller
Journal:  J Small Anim Pract       Date:  1999-08       Impact factor: 1.522

8.  Relationship between histamine release and leukotrienes production from human basophils derived from atopic dermatitis donors.

Authors:  M Shichijo; M Ebisawa; K Miura; Y Toida; T Onda; H Saito; H Nagai; Y Iikura
Journal:  Int Arch Allergy Immunol       Date:  1995-08       Impact factor: 2.749

9.  Diagnosis of food allergy in dogs.

Authors:  E J Rosser
Journal:  J Am Vet Med Assoc       Date:  1993-07-15       Impact factor: 1.936

Review 10.  The role of leukotrienes in inflammation.

Authors:  W R Henderson
Journal:  Ann Intern Med       Date:  1994-11-01       Impact factor: 25.391
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