Literature DB >> 11900881

BRCA1 and BRCA2 in hereditary breast cancer.

Ralph Scully1, Nadine Puget.   

Abstract

The hereditary breast and ovarian cancer susceptibility genes, BRCA1 and BRCA2, have established roles in genome integrity maintenance and in the control of homologous recombination. Recent work has produced valuable insights into the mechanisms of action of the gene products. This review summarizes some of these advances, and attempts to place them in the context of known functions of the genes.

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Year:  2002        PMID： 11900881     DOI： 10.1016/s0300-9084(01)01359-1

Source DB:  PubMed          Journal:  Biochimie        ISSN： 0300-9084            Impact factor:   4.079


  9 in total

1.  Binding and recognition in the assembly of an active BRCA1/BARD1 ubiquitin-ligase complex.

Authors:  Peter S Brzovic; Jennifer R Keeffe; Hiroyuki Nishikawa; Keiko Miyamoto; David Fox; Mamoru Fukuda; Tomohiko Ohta; Rachel Klevit
Journal:  Proc Natl Acad Sci U S A       Date:  2003-05-05       Impact factor: 11.205

Review 2.  Emerging roles of BRCA1 alternative splicing.

Authors:  T I Orban; E Olah
Journal:  Mol Pathol       Date:  2003-08

3.  Presynaptic filament dynamics in homologous recombination and DNA repair.

Authors:  Jie Liu; Kirk T Ehmsen; Wolf-Dietrich Heyer; Scott W Morrical
Journal:  Crit Rev Biochem Mol Biol       Date:  2011-06       Impact factor: 8.250

Review 4.  Hereditary breast and ovarian cancer: review and future perspectives.

Authors:  Michael P Lux; Peter A Fasching; Matthias W Beckmann
Journal:  J Mol Med (Berl)       Date:  2005-11-11       Impact factor: 4.599

5.  Familial breast and bowel cancer: does it exist?

Authors:  Rodney J Scott; Katie A Ashton
Journal:  Hered Cancer Clin Pract       Date:  2004-02-15       Impact factor: 2.857

6.  DNA double strand break repair and its association with inherited predispositions to breast cancer.

Authors:  Rodney J Scott
Journal:  Hered Cancer Clin Pract       Date:  2004-02-15       Impact factor: 2.857

Review 7.  RAD51C: a novel cancer susceptibility gene is linked to Fanconi anemia and breast cancer.

Authors:  Kumar Somyajit; Shreelakshmi Subramanya; Ganesh Nagaraju
Journal:  Carcinogenesis       Date:  2010-10-15       Impact factor: 4.944

8.  Structure of an E3:E2~Ub complex reveals an allosteric mechanism shared among RING/U-box ligases.

Authors:  Jonathan N Pruneda; Peter J Littlefield; Sarah E Soss; Kyle A Nordquist; Walter J Chazin; Peter S Brzovic; Rachel E Klevit
Journal:  Mol Cell       Date:  2012-08-09       Impact factor: 17.970

9.  Association of common variants in mismatch repair genes and breast cancer susceptibility: a multigene study.

Authors:  João Conde; Susana N Silva; Ana P Azevedo; Valdemar Teixeira; Julieta Esperança Pina; José Rueff; Jorge F Gaspar
Journal:  BMC Cancer       Date:  2009-09-25       Impact factor: 4.430
  9 in total

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