| Literature DB >> 11899101 |
David J Kennaway1, Helen Wright.
Abstract
Melatonin synthesis and secretion by the pineal gland is under the control of the suprachiasmatic nucleus and consequently has a profound circadian rhythm. In this review we discuss some of the issues surrounding the measurement of melatonin rhythmicity in biological fluids and the factors that influence melatonin circadian rhythmicity, including light and drugs. We also review the role of melatonin rhythmicity in sleep timing and sleep initiation.Entities:
Mesh:
Substances:
Year: 2002 PMID: 11899101 DOI: 10.2174/1568026023394380
Source DB: PubMed Journal: Curr Top Med Chem ISSN: 1568-0266 Impact factor: 3.295