Literature DB >> 11898480

New antiepileptic drugs: comparative studies of efficacy and cognition.

Steven L Weinstein1, Joan Conry.   

Abstract

Over the past 10 years, the Food and Drug Administration has approved eight prophylactic antiepileptic drugs (AEDs). Although the goal of universal seizure control without side effects has not been reached, the tolerability of medications has improved. This paper reviews the AEDs introduced since 1993 and tries to objectively present comparative data obtained in double-blind studies.

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Year:  2002        PMID: 11898480     DOI: 10.1007/s11910-002-0022-5

Source DB:  PubMed          Journal:  Curr Neurol Neurosci Rep        ISSN: 1528-4042            Impact factor:   5.081


  46 in total

1.  Cognitive and behavioral effects of antiepileptic drugs.

Authors:  K J Meador; F G Gilliam; A M Kanner; J M Pellock
Journal:  Epilepsy Behav       Date:  2001-08       Impact factor: 2.937

2.  Considerations on designing clinical trials to evaluate the place of new antiepileptic drugs in the treatment of newly diagnosed and chronic patients with epilepsy.

Authors: 
Journal:  Epilepsia       Date:  1998-07       Impact factor: 5.864

3.  Cognitive effects of topiramate, gabapentin, and lamotrigine in healthy young adults.

Authors:  R Martin; R Kuzniecky; S Ho; H Hetherington; J Pan; K Sinclair; F Gilliam; E Faught
Journal:  Neurology       Date:  1999-01-15       Impact factor: 9.910

4.  Effects of tiagabine monotherapy on abilities, adjustment, and mood.

Authors:  C B Dodrill; J L Arnett; V Shu; G C Pixton; G T Lenz; K W Sommerville
Journal:  Epilepsia       Date:  1998-01       Impact factor: 5.864

5.  The effects of antiepileptic drugs on cognition in normal volunteers.

Authors:  R Akaho
Journal:  Psychiatry Clin Neurosci       Date:  1996-04       Impact factor: 5.188

6.  Risk of recurrent seizures after two unprovoked seizures.

Authors:  W A Hauser; S S Rich; J R Lee; J F Annegers; V E Anderson
Journal:  N Engl J Med       Date:  1998-02-12       Impact factor: 91.245

7.  Long-term retention rates of lamotrigine, gabapentin, and topiramate in chronic epilepsy.

Authors:  S D Lhatoo; I C Wong; G Polizzi; J W Sander
Journal:  Epilepsia       Date:  2000-12       Impact factor: 5.864

8.  Parent- and patient-validated content for pediatric epilepsy quality-of-life assessment.

Authors:  G Arunkumar; E Wyllie; P Kotagal; H T Ong; F Gilliam
Journal:  Epilepsia       Date:  2000-11       Impact factor: 5.864

9.  Comparison of carbamazepine, phenobarbital, phenytoin, and primidone in partial and secondarily generalized tonic-clonic seizures.

Authors:  R H Mattson; J A Cramer; J F Collins; D B Smith; A V Delgado-Escueta; T R Browne; P D Williamson; D M Treiman; J O McNamara; C B McCutchen
Journal:  N Engl J Med       Date:  1985-07-18       Impact factor: 91.245

10.  A comparison of valproate with carbamazepine for the treatment of complex partial seizures and secondarily generalized tonic-clonic seizures in adults. The Department of Veterans Affairs Epilepsy Cooperative Study No. 264 Group.

Authors:  R H Mattson; J A Cramer; J F Collins
Journal:  N Engl J Med       Date:  1992-09-10       Impact factor: 91.245

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