Literature DB >> 11894902

Evidence for a coupling of synthesis and export of an outer membrane protein in Escherichia coli.

M N Hall1, J Gabay, M Schwartz.   

Abstract

We describe a lesion, lamB701-708, affecting the hydrophilic portion of the lambda receptor signal sequence. The C to A transversion of the sixth codon of the signal sequence changes a positively charged arginine to a neutral serine. The phenotype conferred by this alteration is unique among previously described signal sequence mutations. The results suggest an essential role for the charged amino acids of the hydrophilic segment in the initial interaction between a nascent secreted protein and a membrane export site. The results further suggest that synthesis of lambda receptor is coupled to its export.

Entities:  

Mesh：

Substances：

Year:  1983        PMID： 11894902      PMCID： PMC555079          DOI： 10.1002/j.1460-2075.1983.tb01373.x

Source DB:  PubMed          Journal:  EMBO J        ISSN： 0261-4189            Impact factor:   11.598


  37 in total

1.  Protein Ia and the lamB protein can replace each other in the constitution of an active receptor for the same coliphage.

Authors:  C Wandersman; M Schwartz
Journal:  Proc Natl Acad Sci U S A       Date:  1978-11       Impact factor: 11.205

2.  The outer membrane proteins of Gram-negative bacteria: biosynthesis, assembly, and functions.

Authors:  J M DiRienzo; K Nakamura; M Inouye
Journal:  Annu Rev Biochem       Date:  1978       Impact factor: 23.643

3.  Use of gene fusions to study outer membrane protein localization in Escherichia coli.

Authors:  T J Silhavy; H A Shuman; J Beckwith; M Schwartz
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205

4.  A possible precursor of immunoglobulin light chains.

Authors:  C Milstein; G G Brownlee; T M Harrison; M B Mathews
Journal:  Nat New Biol       Date:  1972-09-27

5.  A film detection method for tritium-labelled proteins and nucleic acids in polyacrylamide gels.

Authors:  W M Bonner; R A Laskey
Journal:  Eur J Biochem       Date:  1974-07-01

6.  Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors:  U K Laemmli
Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

7.  Maltose transport in Escherichia coli K-12: involvement of the bacteriophage lambda receptor.

Authors:  S Szmelcman; M Hofnung
Journal:  J Bacteriol       Date:  1975-10       Impact factor: 3.490

8.  Isolation of the bacteriophage lambda receptor from Escherichia coli.

Authors:  L Randall-Hazelbauer; M Schwartz
Journal:  J Bacteriol       Date:  1973-12       Impact factor: 3.490

9.  Pattern of protein synthesis in monkey cells infected by simian virus 40.

Authors:  C W Anderson; R F Gesteland
Journal:  J Virol       Date:  1972-05       Impact factor: 5.103

10.  Transfer of proteins across membranes. I. Presence of proteolytically processed and unprocessed nascent immunoglobulin light chains on membrane-bound ribosomes of murine myeloma.

Authors:  G Blobel; B Dobberstein
Journal:  J Cell Biol       Date:  1975-12       Impact factor: 10.539
View more
  29 in total

1.  Alterations in the hydrophilic segment of the maltose-binding protein (MBP) signal peptide that affect either export or translation of MBP.

Authors:  J W Puziss; R J Harvey; P J Bassford
Journal:  J Bacteriol       Date:  1992-10       Impact factor: 3.490

Review 2.  The sec and prl genes of Escherichia coli.

Authors:  K L Bieker; G J Phillips; T J Silhavy
Journal:  J Bioenerg Biomembr       Date:  1990-06       Impact factor: 2.945

3.  Analysis of mutational alterations in the hydrophilic segment of the maltose-binding protein signal peptide.

Authors:  J W Puziss; J D Fikes; P J Bassford
Journal:  J Bacteriol       Date:  1989-05       Impact factor: 3.490

4.  Lethal mutations in the structural gene of an outer membrane protein (OmpA) of Escherichia coli K12.

Authors:  R Freudl; G Braun; I Hindennach; U Henning
Journal:  Mol Gen Genet       Date:  1985

5.  Does secA mediate coupling between secretion and translation in Escherichia coli?

Authors:  K L Strauch; C A Kumamoto; J Beckwith
Journal:  J Bacteriol       Date:  1986-05       Impact factor: 3.490

6.  Translational control of exported proteins in Escherichia coli.

Authors:  R Hengge-Aronis; W Boos
Journal:  J Bacteriol       Date:  1986-08       Impact factor: 3.490

7.  Nucleotide sequence and transcriptional analysis of the E. coli ushA gene, encoding periplasmic UDP-sugar hydrolase (5'-nucleotidase): regulation of the ushA gene, and the signal sequence of its encoded protein product.

Authors:  D M Burns; I R Beacham
Journal:  Nucleic Acids Res       Date:  1986-05-27       Impact factor: 16.971

8.  Mutations affecting the signal sequence alter synthesis and secretion of yeast invertase.

Authors:  D Perlman; P Raney; H O Halvorson
Journal:  Proc Natl Acad Sci U S A       Date:  1986-07       Impact factor: 11.205

9.  Effects of signal sequence mutations on the kinetics of alkaline phosphatase export to the periplasm in Escherichia coli.

Authors:  S Michaelis; J F Hunt; J Beckwith
Journal:  J Bacteriol       Date:  1986-07       Impact factor: 3.490

10.  Secretion-defective mutations in the signal sequence for Saccharomyces cerevisiae invertase.

Authors:  C A Kaiser; D Botstein
Journal:  Mol Cell Biol       Date:  1986-07       Impact factor: 4.272
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.