A survey of the pattern of glandular distribution in the larynges of human infants.

We studied the development of glandular structures and the pattern of distribution of serous and mucous-type glands in the larynges of 77 human infants obtained at autopsy. The subglottic larynx was subjected to quantitative and qualitative analysis, using an image binarization procedure. The areas of mucosa and inner space of the subglottic larynx tended to increase with age. The area occupied by the glands differed considerably in younger infants and the areas of total glands and serous-type glands increased with age. There was no correlation between the area of the mucous glands and age. These findings indicate that local immune function of the secretory glandular system in the larynx of human infants increases with advancing age.