Literature DB >> 11893894

Cervical intramedullary gliofibroma in a child: a case report and review of the literature.

Akira Matsumura1, Shingo Takano, Michio Nagata, Izumi Anno, Tadao Nose.   

Abstract

A rare case of intramedullary gliofibroma in a 12-year-old girl is reported. MRI revealed an intramedullary tumor with two different intensities, and these portions showed different staining patterns after gadolinium contrast enhancement, with faint enhancement at the periphery and strong enhancement in the central portion. Intraoperatively, the tumor had a relatively clear margin to the spinal cord and was composed of two portions of different consistencies, one soft in the periphery and the other elastic and firm in the central portion. This tumor was grossly, totally removed. The patient made a full recovery and there was no recurrence 2 years and 9 months after operation. There have only been 7 previous case reports of spinal intramedullary gliofibroma. Gliofibroma is usually a relatively benign astroglial variant. Recognition of such a variant is clinically important in considering the extent of the operation and postoperative adjuvant therapy. Copyright 2002 S. Karger AG, Basel

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Year:  2002        PMID: 11893894     DOI: 10.1159/000048362

Source DB:  PubMed          Journal:  Pediatr Neurosurg        ISSN: 1016-2291            Impact factor:   1.162


  4 in total

1.  Rare Pediatric Invasive Gliofibroma Has BRAFV600E Mutation and Transiently Responds to Targeted Therapy Before Progressive Clonal Evolution.

Authors:  Kristiyana Kaneva; Kee Kiat Yeo; Debra Hawes; Jianling Ji; Jaclyn A Biegel; Marvin D Nelson; Stefan Bluml; Mark D Krieger; Anat Erdreich-Epstein
Journal:  JCO Precis Oncol       Date:  2019-03-27

2.  WHO Grade IV Gliofibroma: A Grading Label Denoting Malignancy for an Otherwise Commonly Misinterpreted Neoplasm.

Authors:  Paola A Escalante Abril; Miguel Fdo Salazar; Nubia L López García; Mónica N Madrazo Moya; Yadir U Zamora Guerra; Yadira Gandhi Mata Mendoza; Erick Gómez Apo; Laura G Chávez Macías
Journal:  J Pathol Transl Med       Date:  2015-07-15

3.  Intracranial gliofibroma: a case report and review of the literature.

Authors:  Patricia Gargano; Graciela Zuccaro; Fabiana Lubieniecki
Journal:  Case Rep Pathol       Date:  2014-07-13

4.  Adult Intracranial Gliofibroma : A Case Report and Review of the Literature.

Authors:  Ho Kang; Jin Wook Kim; Young-Bem Se; Sung-Hye Park
Journal:  J Korean Neurosurg Soc       Date:  2016-05-10
  4 in total

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