Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Asthma genetics.

Literature DB >> 11893653

Asthma genetics.

Abstract

Asthma is the most common chronic childhood disease in developed nations and is a complex disease that has high social and economic costs. Asthma and its associated intermediate phenotypes are under a substantial degree of genetic control. Identifying the genes underlying asthma offers a means of better understanding its pathogenesis, with the promise of improving preventive strategies, diagnostic tools, and therapies. A number of chromosomal regions containing genes influencing asthma and atopy have been identified consistently by different groups, and a role for several candidate genes has been established.

Entities: Disease

Mesh：

Substances：

Year: 2002 PMID： 11893653 DOI： 10.1378/chest.121.3_suppl.7s-a

Source DB: PubMed Journal: Chest ISSN： 0012-3692 Impact factor: 9.410

Keyword Cloud
Cited

14 in total

1. Genetic evidence for interaction of the 5q31 cytokine locus and the CARD15 gene in Crohn disease.

Authors: Muddassar M Mirza; Sheila A Fisher; Kathy King; Andrew P Cuthbert; Jochen Hampe; Jeremy Sanderson; John Mansfield; Peter Donaldson; Andrew J S Macpherson; Alastair Forbes; Stefan Schreiber; Cathryn M Lewis; Christopher G Mathew
Journal: Am J Hum Genet Date: 2003-03-03 Impact factor: 11.025

2. Use of multivariate linkage analysis for dissection of a complex cognitive trait.

Authors: Angela J Marlow; Simon E Fisher; Clyde Francks; I Laurence MacPhie; Stacey S Cherny; Alex J Richardson; Joel B Talcott; John F Stein; Anthony P Monaco; Lon R Cardon
Journal: Am J Hum Genet Date: 2003-02-13 Impact factor: 11.025

3. A sequence variant on 17q21 is associated with age at onset and severity of asthma.

Authors: Eva Halapi; Daniel F Gudbjartsson; Gudrun M Jonsdottir; Unnur S Bjornsdottir; Gudmar Thorleifsson; Hafdis Helgadottir; Carolyn Williams; Gerard H Koppelman; Andrea Heinzmann; H Marike Boezen; Aslaug Jonasdottir; Thorarinn Blondal; Sigurjon A Gudjonsson; Adalbjorg Jonasdottir; Theodora Thorlacius; Amanda P Henry; Janine Altmueller; Marcus Krueger; Hyoung Doo Shin; Soo-Taek Uh; Hyun Sub Cheong; Brynja Jonsdottir; Bjorn R Ludviksson; Dora Ludviksdottir; David Gislason; Choon-Sik Park; Klaus Deichmann; Philip J Thompson; Matthias Wjst; Ian P Hall; Dirkje S Postma; Thorarinn Gislason; Augustine Kong; Ingileif Jonsdottir; Unnur Thorsteinsdottir; Kari Stefansson
Journal: Eur J Hum Genet Date: 2010-04-07 Impact factor: 4.246

4. Lack of association between asthma and ABO blood group.

Authors: Mahdi Bijanzadeh; Nallur B Ramachandra; P A Mahesh; Mysore R Savitha; B S Manjunath; B S Jayaraj
Journal: Lung Date: 2009-09-22 Impact factor: 2.584

5. Association of interleukin-18 gene polymorphism with asthma in Chinese patients.

Authors: Cheng-Chun Lee; Wei-Yong Lin; Lei Wan; Yuhsin Tsai; Chang-Hai Tsai; Chung-Ming Huang; Chih-Ping Chen; Fuu-Jen Tsai
Journal: J Clin Lab Anal Date: 2008 Impact factor: 2.352

6. Relationship between urinary cysteinyl leukotriene E4 levels and clinical response to antileukotriene treatment in patients with asthma.

Authors: Chang Cai; Jiong Yang; Suping Hu; Meiqian Zhou; Wei Guo
Journal: Lung Date: 2007-03-28 Impact factor: 2.584

Asthma genetics.

1. Genetic evidence for interaction of the 5q31 cytokine locus and the CARD15 gene in Crohn disease.

2. Use of multivariate linkage analysis for dissection of a complex cognitive trait.

3. A sequence variant on 17q21 is associated with age at onset and severity of asthma.

4. Lack of association between asthma and ABO blood group.

5. Association of interleukin-18 gene polymorphism with asthma in Chinese patients.

6. Relationship between urinary cysteinyl leukotriene E4 levels and clinical response to antileukotriene treatment in patients with asthma.

7. Glutathione S-transferase P1, maternal smoking, and asthma in children: a haplotype-based analysis.

8. Multivariate association test using haplotype trend regression.

9. Allergen-specific subcutaneous immunotherapy in allergic asthma: immunologic mechanisms and improvement.

Review 10. An understanding of the genetic basis of asthma.