Joseph Rinaggio1, H Stan McGuff, Randal Otto, Charlene Hickson. 1. Department of Oral Pathology, Biology, and Diagnostic Sciences, Rm. C-829, University of Medicine and Dentistry of New Jersey---New Jersey Dental School, 110 Bergen Street, Newark, NJ 07103-2400, USA.
Abstract
BACKGROUND: Sebaceous carcinoma is an uncommon malignant neoplasm usually associated with the ocular adnexa. Despite the widespread anatomic distribution of sebaceous glands, extraocular sebaceous carcinoma occurs with far less frequency. METHODS: A 27-year-old man was examined with the presenting complaint of a slowly enlarging subcutaneous mass. It was associated with an overlying, irregular, verrucoid epidermal plaque. RESULTS: Histologic and electron microscopic examination of the mass revealed a malignant sebaceous neoplasm occurring in conjunction with an overlying nevus sebaceus. The dermal neoplasm contained numerous cytoplasmic and stromal hyaline globules. CONCLUSIONS: We report a case of extraocular sebaceous carcinoma arising in the postauricular region in association with a nevus sebaceus and exhibiting the unusual histologic feature of hyaline globules.
BACKGROUND:Sebaceous carcinoma is an uncommon malignant neoplasm usually associated with the ocular adnexa. Despite the widespread anatomic distribution of sebaceous glands, extraocular sebaceous carcinoma occurs with far less frequency. METHODS: A 27-year-old man was examined with the presenting complaint of a slowly enlarging subcutaneous mass. It was associated with an overlying, irregular, verrucoid epidermal plaque. RESULTS: Histologic and electron microscopic examination of the mass revealed a malignant sebaceous neoplasm occurring in conjunction with an overlying nevus sebaceus. The dermal neoplasm contained numerous cytoplasmic and stromal hyaline globules. CONCLUSIONS: We report a case of extraocular sebaceous carcinoma arising in the postauricular region in association with a nevus sebaceus and exhibiting the unusual histologic feature of hyaline globules.
Authors: Răzvan Mercuţ; Mihaela Ionescu; Cristiana Simionescu; Vlad Pîrvănescu; Maria Filoftea Mercuţ; Alexandru Gogănău; Marius Eugen Ciurea Journal: Curr Health Sci J Date: 2021-12-31