| Literature DB >> 11891347 |
Matthew Fury1, Steven O Marx, Andrew R Marks.
Abstract
The activity of ion channels is regulated by several different mechanisms. Studies have been undertaken to determine how the large-conductance Ca(2+)-sensitive K(+) channel (the BK channel) is regulated. Fury et al. discuss how the presence or absence of alternatively spliced regions in the BK channel alpha subunit can act as a molecular switch by which different kinases activate the BK channel.Entities:
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Year: 2002 PMID： 11891347 DOI： 10.1126/stke.2002.123.pe12
Source DB: PubMed Journal: Sci STKE ISSN： 1525-8882