Literature DB >> 11891115

Live-cell fluorescent biosensors for activated signaling proteins.

Klaus Hahn1, Alexei Toutchkine.   

Abstract

A new generation of live-cell fluorescent biosensors enables us to go beyond visualization of protein movements, to quantify the dynamics of many different protein activities. Alternate approaches can report post-translational modifications, ligand interactions and conformational changes, revealing how the location and subtle timing of protein activity controls cell behavior.

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Year:  2002        PMID： 11891115     DOI： 10.1016/s0955-0674(02)00313-7

Source DB:  PubMed          Journal:  Curr Opin Cell Biol        ISSN： 0955-0674            Impact factor:   8.382


  9 in total

1.  Imaging of metabolites by using a fusion protein between a periplasmic binding protein and GFP derivatives: from a chimera to a view of reality.

Authors:  Mark Stitt
Journal:  Proc Natl Acad Sci U S A       Date:  2002-07-15       Impact factor: 11.205

2.  Minimal determinants for binding activated G alpha from the structure of a G alpha(i1)-peptide dimer.

Authors:  Christopher A Johnston; Ekaterina S Lobanova; Alexander S Shavkunov; Justin Low; J Kevin Ramer; Rainer Blaesius; Zoey Fredericks; Francis S Willard; Brian Kuhlman; Vadim Y Arshavsky; David P Siderovski
Journal:  Biochemistry       Date:  2006-09-26       Impact factor: 3.162

3.  Experimental and DFT studies: novel structural modifications greatly enhance the solvent sensitivity of live cell imaging dyes.

Authors:  Alexei Toutchkine; Wen-Ge Han; Matthias Ullmann; Tiqing Liu; Donald Bashford; Louis Noodleman; Klaus M Hahn
Journal:  J Phys Chem A       Date:  2007-10-05       Impact factor: 2.781

Review 4.  The spatiotemporal organization of ErbB receptors: insights from microscopy.

Authors:  Christopher C Valley; Keith A Lidke; Diane S Lidke
Journal:  Cold Spring Harb Perspect Biol       Date:  2014-02-01       Impact factor: 10.005

5.  Visualization of small GTPase activity with fluorescence resonance energy transfer-based biosensors.

Authors:  Kazuhiro Aoki; Michiyuki Matsuda
Journal:  Nat Protoc       Date:  2009-10-15       Impact factor: 13.491

6.  Environment-sensing merocyanine dyes for live cell imaging applications.

Authors:  Christopher J MacNevin; Dmitriy Gremyachinskiy; Chia-Wen Hsu; Li Li; Marie Rougie; Tamara T Davis; Klaus M Hahn
Journal:  Bioconjug Chem       Date:  2013-01-16       Impact factor: 4.774

7.  Biosensor Förster resonance energy transfer detection by the phasor approach to fluorescence lifetime imaging microscopy.

Authors:  Elizabeth Hinde; Michelle A Digman; Christopher Welch; Klaus M Hahn; Enrico Gratton
Journal:  Microsc Res Tech       Date:  2011-08-19       Impact factor: 2.769

8.  Membrane-Permeant, Environment-Sensitive Dyes Generate Biosensors within Living Cells.

Authors:  Christopher J MacNevin; Takashi Watanabe; Matthew Weitzman; Akash Gulyani; Sheryl Fuehrer; Nicholas K Pinkin; Xu Tian; Feng Liu; Jian Jin; Klaus M Hahn
Journal:  J Am Chem Soc       Date:  2019-04-23       Impact factor: 15.419

9.  Quantitative ratiometric imaging of FRET-biosensors in living cells.

Authors:  Désirée Spiering; Jose Javier Bravo-Cordero; Yasmin Moshfegh; Veronika Miskolci; Louis Hodgson
Journal:  Methods Cell Biol       Date:  2013       Impact factor: 1.441
  9 in total

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