Literature DB >> 11890619

Acute cholecystitis--room for improvement?

I C Cameron1, C Chadwick, J Phillips, A G Johnson.   

Abstract

AIMS: A recent survey of UK general surgeons showed that almost 90% prefer to manage patients with acute cholecystitis by initial conservative management and delayed cholecystectomy (DC). The aim of this study was to assess the effectiveness of this management policy in a large university hospital. PATIENTS AND METHODS: All patients admitted with acute cholecystitis between January 1997 and June 1999 who went on to have a cholecystectomy were identified. Patients were required to have right upper quadrant pain for > 12 h, a raised white cell count and findings consistent with acute cholecystitis on ultrasound to be included in the study.
RESULTS: 109 patients were admitted with acute cholecystitis (76 female, 33 male) with a median age of 62 years (range, 22-88 years). Conservative management failed in 16 patients (14.7%) who underwent emergency cholecystectomy due to continuing symptoms (9), empyema (4) and peritonitis (3). Symptoms settled in 93 patients and delayed cholecystectomy was performed without further problems in 66 (60.6%). 27 patients were re-admitted with further symptoms before their elective surgery and, of these, 3 were admitted for a third time before surgical intervention. Ten of the 30 re-admission episodes (33%) occurred within 3 weeks of discharge but 15 (56%) occurred more than 2 months after discharge. Elective surgery was undertaken at a median of 10 weeks post-discharge with 67% of operations occurring within 3 months. Mean total hospital stay (days) +/- SEM, for the three groups were: emergency surgery group, 10.21 +/- 0.85; uncomplicated DC group, 12.48 +/- 0.37; re-admitted group, 14.75 +/- 0.71.
CONCLUSIONS: The policy of conservative management and DC was successful in 60.6% of cases but 14.7% of patients required emergency surgery and 24.8% were re-admitted prior to elective surgery with a resultant increase in total hospital stay. Performing elective surgery within 2 months of discharge in all cases would have reduced the re-admission rate by 56% and this along with the increased use of early cholecystectomy during the first admission are areas where the treatment of acute cholecystitis could be significantly improved.

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Year:  2002        PMID: 11890619      PMCID: PMC2503755     

Source DB:  PubMed          Journal:  Ann R Coll Surg Engl        ISSN: 0035-8843            Impact factor:   1.891


  13 in total

1.  Early laparoscopic cholecystectomy for acute cholecystitis: a safe procedure.

Authors:  P C Willsher; J R Sanabria; S Gallinger; L Rossi; S Strasberg; D E Litwin
Journal:  J Gastrointest Surg       Date:  1999 Jan-Feb       Impact factor: 3.452

2.  Laparoscopic cholecystectomy for acute cholecystitis: prospective trial.

Authors:  S Eldar; E Sabo; E Nash; J Abrahamson; I Matter
Journal:  World J Surg       Date:  1997-06       Impact factor: 3.352

3.  Laparoscopic management of acute cholecystitis. Prognostic factors for success.

Authors:  A Bickel; A Rappaport; V Kanievski; I Vaksman; M Haj; N Geron; A Eitan
Journal:  Surg Endosc       Date:  1996-11       Impact factor: 4.584

4.  Laparoscopic cholecystectomy in acute cholecystitis. What is the optimal timing for operation?

Authors:  K P Koo; R C Thirlby
Journal:  Arch Surg       Date:  1996-05

5.  Early or delayed cholecystectomy in acute cholecystitis? A clinical trial.

Authors:  S Norrby; P Herlin; T Holmin; R Sjödahl; C Tagesson
Journal:  Br J Surg       Date:  1983-03       Impact factor: 6.939

6.  Laparoscopic cholecystectomy in the treatment of acute cholecystitis.

Authors:  J A Lujan; P Parrilla; R Robles; J A Torralba; J Garcia Ayllon; R Liron; F Sanchez-Bueno
Journal:  J Am Coll Surg       Date:  1995-07       Impact factor: 6.113

7.  Laparoscopic cholecystectomy for acute cholecystitis: is it really safe?

Authors:  C K Kum; E Eypasch; R Lefering; A Paul; E Neugebauer; H Troidl
Journal:  World J Surg       Date:  1996-01       Impact factor: 3.352

8.  Early cholecystectomy for acute cholecystitis: a prospective randomized study.

Authors:  H J Järvinen; J Hästbacka
Journal:  Ann Surg       Date:  1980-04       Impact factor: 12.969

9.  The Baltimore experience with laparoscopic management of acute cholecystitis.

Authors:  J L Flowers; R W Bailey; W A Scovill; K A Zucker
Journal:  Am J Surg       Date:  1991-03       Impact factor: 2.565

10.  Bile duct injuries, 1989-1993. A statewide experience. Connecticut Laparoscopic Cholecystectomy Registry.

Authors:  J C Russell; S J Walsh; A S Mattie; J T Lynch
Journal:  Arch Surg       Date:  1996-04
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  11 in total

1.  Management of acute cholecystitis in UK hospitals: time for a change.

Authors:  I C Cameron; C Chadwick; J Phillips; A G Johnson
Journal:  Postgrad Med J       Date:  2004-05       Impact factor: 2.401

2.  Early cholecystectomy after acute admission with cholecystitis: how much work?

Authors:  Michael R Stephens; Ceri Beaton; Adrian C Steger
Journal:  World J Surg       Date:  2010-09       Impact factor: 3.352

3.  Role of Procalcitonin in Evaluation of the Severity of Acute Cholecystitis.

Authors:  Yucel Yuzbasioglu; Hikmet Duymaz; Ceren Sen Tanrikulu; Huseyin Cahit Halhalli; Mirac Ozturk Koc; Meral Tandoğan; Figen Coskun
Journal:  Eurasian J Med       Date:  2016-10

4.  Delay from symptom onset increases the conversion rate in laparoscopic cholecystectomy for acute cholecystitis.

Authors:  Sirwan M Hadad; Jayant S Vaidya; Lee Baker; Hoey C Koh; Timothy P Heron; Kashif Hussain; Alastair M Thompson
Journal:  World J Surg       Date:  2007-06       Impact factor: 3.352

5.  Low ninety-day re-admission rates after emergency and elective laparoscopic cholecystectomy in a district general hospital.

Authors:  Sue K Down; Marko Nicolic; Hibba Abdulkarim; Nick Skelton; Adrian H Harris; Yashwant Koak
Journal:  Ann R Coll Surg Engl       Date:  2010-05       Impact factor: 1.891

6.  Percutaneous aspiration of the gall bladder for the treatment of acute cholecystitis: a prospective study.

Authors:  Ilana Haas; Elon Lahat; Ygal Griton; Pavel Shmulevsky; Stanislav Shichman; Guy Elad; Chagay Kammar; Ori Yaslovich; Shai Kendror; Anat Ben-Ari; Haim Paran
Journal:  Surg Endosc       Date:  2015-07-23       Impact factor: 4.584

7.  Urgent cholecystectomy for acute cholecystitis in a district general hospital - is it feasible?

Authors:  M N Khan; I Nordon; A S K Ghauri; C Ranaboldo; N Carty
Journal:  Ann R Coll Surg Engl       Date:  2008-11-04       Impact factor: 1.891

Review 8.  Laparoscopic cholecystectomy in acute cholecystitis: indication, technique, risk and outcome.

Authors:  U Giger; J M Michel; R Vonlanthen; K Becker; T Kocher; L Krähenbühl
Journal:  Langenbecks Arch Surg       Date:  2004-08-14       Impact factor: 3.445

9.  Gallstones: best served hot.

Authors:  Tarun Singhal; Santosh Balakrishnan; Starlene Grandy-Smith; John Hunt; Maxwell Asante; Shamsi El-Hasani
Journal:  JSLS       Date:  2006 Jul-Sep       Impact factor: 2.172

10.  Is sentinel lymph node mapping in colorectal cancer a future prognostic factor? A meta-analysis.

Authors:  Gaëtan Des Guetz; Bernard Uzzan; Patrick Nicolas; Michel Cucherat; Philippe de Mestier; Jean-François Morere; Jean-Luc Breau; Gérard Perret
Journal:  World J Surg       Date:  2007-06       Impact factor: 3.282

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