| Literature DB >> 11889593 |
Burkhard Helpap1, Günter Klöppel.
Abstract
This review addresses the various morphological, immunohistochemical and cell kinetic aspects of pure and mixed neuroendocrine carcinomas of the prostate and urinary bladder and of carcinomas with focal neuroendocrine differentiation. It is important that neuroendocrine tumours of the prostate and urinary bladder be clearly distinguished from their nonneuroendocrine counterparts because of differences in treatment and prognosis. In the case of high-grade neuroendocrine carcinomas, early diagnosis and initiation of appropriate chemotherapy may increase survival and potentially induce complete remission in individual cases.Entities:
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Year: 2002 PMID: 11889593 DOI: 10.1007/s00428-001-0583-8
Source DB: PubMed Journal: Virchows Arch ISSN: 0945-6317 Impact factor: 4.064