Literature DB >> 11889082

Hepatic stellate cells: role in microcirculation and pathophysiology of portal hypertension.

H Reynaert1, M G Thompson, T Thomas, A Geerts.   

Abstract

Accumulating evidence suggests that stellate cells are involved in the regulation of the liver microcirculation and portal hypertension. Activated hepatic stellate cells have the necessary machinery to contract or relax in response to a number of vasoactive substances. Because stellate cells play a role in both fibrosis and portal hypertension, they are currently regarded as therapeutic targets to prevent and treat the complications of chronic liver disease.

Entities:  

Mesh：

Substances：

Year:  2002        PMID： 11889082      PMCID： PMC1773176          DOI： 10.1136/gut.50.4.571

Source DB:  PubMed          Journal:  Gut        ISSN： 0017-5749            Impact factor:   23.059


  146 in total

Review 1.  Morphological mechanisms for regulating blood flow through hepatic sinusoids.

Authors:  R S McCuskey
Journal:  Liver       Date:  2000-02

2.  Direct measurement of blood pressures in minute vessels of the liver.

Authors:  K NAKATA; G F LEONG; R W BRAUER
Journal:  Am J Physiol       Date:  1960-12

Review 3.  The nitric oxide synthase family of proteins.

Authors:  W C Sessa
Journal:  J Vasc Res       Date:  1994 May-Jun       Impact factor: 1.934

4.  Differential involvement of Galpha12 and Galpha13 in receptor-mediated stress fiber formation.

Authors:  A Gohla; S Offermanns; T M Wilkie; G Schultz
Journal:  J Biol Chem       Date:  1999-06-18       Impact factor: 5.157

5.  Biological effects of C-type natriuretic peptide in human myofibroblastic hepatic stellate cells.

Authors:  J Tao; A Mallat; C Gallois; S Belmadani; P F Méry; J T Nhieu; C Pavoine; S Lotersztajn
Journal:  J Biol Chem       Date:  1999-08-20       Impact factor: 5.157

6.  Atrial natriuretic peptide antagonizes endothelin-induced calcium increase and cell contraction in cultured human hepatic stellate cells.

Authors:  M N Görbig; P Ginès; R Bataller; J M Nicolás; E Garcia-Ramallo; E Tobías; E Titos; M J Rey; J Clària; V Arroyo; J Rodés
Journal:  Hepatology       Date:  1999-08       Impact factor: 17.425

7.  Quantitation of rat hepatic stellate cell contraction: stellate cells' contribution to sinusoidal resistance.

Authors:  M S Thimgan; H F Yee
Journal:  Am J Physiol       Date:  1999-07

8.  Inhibition of hepatic stellate cell contraction during activation in vitro by vascular endothelial growth factor in association with upregulation of FLT tyrosine kinase receptor family, FLT-1.

Authors:  S Mashiba; S Mochida; K Ishikawa; M Inao; A Matsui; A Ohno; H Ikeda; S Nagoshi; M Shibuya; K Fujiwara
Journal:  Biochem Biophys Res Commun       Date:  1999-05-19       Impact factor: 3.575

9.  Gene transfer of the neuronal NO synthase isoform to cirrhotic rat liver ameliorates portal hypertension.

Authors:  Q Yu; R Shao; H S Qian; S E George; D C Rockey
Journal:  J Clin Invest       Date:  2000-03       Impact factor: 14.808

10.  Functional significance of endothelin B receptors in mediating sinusoidal and extrasinusoidal effects of endothelins in the intact rat liver.

Authors:  M Bauer; I Bauer; N V Sonin; N Kresge; R Baveja; Y Yokoyama; D Harding; J X Zhang; M G Clemens
Journal:  Hepatology       Date:  2000-04       Impact factor: 17.425
View more
  76 in total

1.  Stellate cells in the digestive tract.

Authors:  Hendrik Reynaert; Filip Sermon; Daniel Urbain; Albert Geerts
Journal:  Curr Gastroenterol Rep       Date:  2003-06

2.  Epigenetic repression of matrix metalloproteinases in myofibroblastic hepatic stellate cells through histone deacetylases 4: implication in tissue fibrosis.

Authors:  Lan Qin; Yuan-Ping Han
Journal:  Am J Pathol       Date:  2010-09-16       Impact factor: 4.307

Review 3.  Regulation of hepatic blood flow: the hepatic arterial buffer response revisited.

Authors:  Christian Eipel; Kerstin Abshagen; Brigitte Vollmar
Journal:  World J Gastroenterol       Date:  2010-12-28       Impact factor: 5.742

4.  MiR-9a-5p regulates proliferation and migration of hepatic stellate cells under pressure through inhibition of Sirt1.

Authors:  Feng Qi; Jiang-Feng Hu; Bao-Hai Liu; Chao-Qun Wu; Hong-Yu Yu; Ding-Kang Yao; Liang Zhu
Journal:  World J Gastroenterol       Date:  2015-09-14       Impact factor: 5.742

5.  Knockdown of Astrocyte Elevated Gene-1 Inhibits Activation of Hepatic Stellate Cells.

Authors:  Lei Chen; Yong-Ze Guo; Ai-di Li; Jun-Ji Ma; Hui-Yao Hao; Di Zhang; Yan Wang; Chen-Guang Ji; Wei Qi; Jia Wang; Hui-Qing Jiang
Journal:  Dig Dis Sci       Date:  2016-02-15       Impact factor: 3.199

6.  Suppression of hedgehog signaling regulates hepatic stellate cell activation and collagen secretion.

Authors:  Tao Li; Xi-Sheng Leng; Ji-Ye Zhu; Gang Wang
Journal:  Int J Clin Exp Pathol       Date:  2015-11-01

7.  Prostaglandin E2 induces contraction of liver myofibroblasts by activating EP3 and FP prostanoid receptors.

Authors:  S Ayabe; T Murata; T Maruyama; M Hori; H Ozaki
Journal:  Br J Pharmacol       Date:  2009-02-23       Impact factor: 8.739

8.  Clinical associations of hepatic stellate cell (HSC) hyperplasia.

Authors:  Taofic Mounajjed; Rondell P Graham; Schuyler O Sanderson; Thomas C Smyrk
Journal:  Virchows Arch       Date:  2014-05-09       Impact factor: 4.064

9.  Hemodynamic and antifibrotic effects of a selective liver nitric oxide donor V-PYRRO/NO in bile duct ligated rats.

Authors:  Frédéric Moal; Nary Veal; Eric Vuillemin; Eric Barrière; Jianhua Wang; Lionel Fizanne; Frédéric Oberti; Olivier Douay; Yves Gallois; Dominique Bonnefont-Rousselot; Marie Christine Rousselet; Paul Calès
Journal:  World J Gastroenterol       Date:  2006-11-07       Impact factor: 5.742

10.  Resident mesenchymal cells and fibrosis.

Authors:  Nicol Hutchison; Cécile Fligny; Jeremy S Duffield
Journal:  Biochim Biophys Acta       Date:  2012-12-04
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.