Pulp-dentin biology in restorative dentistry. Part 6: Reactions to restorative materials, tooth-restoration interfaces, and adhesive techniques.

A number of defense mechanisms may be activated in conjunction with restorative dental treatment. Tissue changes that lead to reduced dentinal permeability are important to minimize pulpal reactions. The healing potentials of the pulp-dentin complex are significant, and restorative dentistry is dependent on the available defense reactions. Clinicians should intentionally include considerations of these reactions in their treatment planning and during restorative treatment.