Literature DB >> 11885882

Malignant colorectal tumours: a ten year review in Jos, Nigeria.

A Z Sule1, B M Mandong, D Iya.   

Abstract

One hundred and forty-four cases of histologically confirmed colorectal cancer in patients managed at the Jos University Teaching Hospital (JUTH) over a 10 year period from January, 1989 to January, 1999 is discussed with special consideration to incidence, distribution and unfavourable prognosis. Altogether, 144 patients were treated for colorectal carcinoma. Eighty-seven were males while fifty-seven were females, giving a male to female ratio of 1.51:1. The mean age was 44.3 years. The commonest clinical presenting features were weight loss, bloody mucoid diarrhoea, anorectal mass, anaemia, low-back pain and constipation/increased noise in the abdomen, present for not less than 3 months. The rectum and rectosigmoid junction were the commonly affected sites. All, except four patients, had advanced disease at first presentation. Treatment was basically palliative with only 43.5 percent of those offered such treatment alive at 6 months while 25 percent had died. Prognosis is unfavourable. Though, predisposing factors are not clear, promotion of educational programme highlighting the dangers of concealing chronic large bowel symptoms and screening efforts will most probably reduce morbidity and mortality rates associated with this condition.

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Mesh:

Year:  2001        PMID: 11885882

Source DB:  PubMed          Journal:  West Afr J Med        ISSN: 0189-160X


  9 in total

1.  A comparison of colorectal cancer in Nigerian and North American patients: is the cancer biology different?

Authors:  Saurabh Saluja; Olusegun I Alatise; Adisa Adewale; Justine Misholy; Joanne Chou; Mithat Gonen; Martin Weiser; T Peter Kingham
Journal:  Surgery       Date:  2014-06-19       Impact factor: 3.982

Review 2.  Immunohistochemical study of MUC1, MUC2 and MUC5AC in colorectal carcinoma and review of literature.

Authors:  Mrunal V Kesari; Vandana L Gaopande; Avinash R Joshi; Shreedhar V Babanagare; Bageshree P Gogate; Ameya V Khadilkar
Journal:  Indian J Gastroenterol       Date:  2015-03-04

3.  Colorectal carcinoma in Lagos and Sagamu, Southwest Nigeria: a histopathological review.

Authors:  Fatimah-Biade Abdulkareem; Emmanuel-Kunle Abudu; Nicholas-Awodele Awolola; Stephen-Olafimihan Elesha; Olorunda Rotimi; Olakanmi-Raphael Akinde; Ayoola-Oluwole Atoyebi; Adedoyin-Adekunle Adesanya; Adetola-Olubunmi Daramola; Adekumbiola-Aina-Fehintola Banjo; Charles-Chidozie Anunobi
Journal:  World J Gastroenterol       Date:  2008-11-14       Impact factor: 5.742

4.  Familial adenomatous polyposis with synchronous invasive colonic carcinomas and metastatic jejunal adenocarcinoma in a Nigerian male.

Authors:  Chukwuemeka C Osuagwu; Okechukwu C Okafor; Emmanuel R Ezeome; Chrisogonus E Uche; Charles Ememonu; Emeka Kesieme
Journal:  Rare Tumors       Date:  2010-12-31

5.  Colorectal carcinoma: why is there a lower incidence in Nigerians when compared to Caucasians?

Authors:  David Omoareghan Irabor
Journal:  J Cancer Epidemiol       Date:  2011-12-29

6.  [Analysis of histoprognostic factors for the non metastatic rectal cancer in a west Algerian series of 58 cases].

Authors:  Smain Nabil Mesli; Derbali Regagba; Anisse Tidjane; Mokhtar Benkalfat; Chakib Abi-Ayad
Journal:  Pan Afr Med J       Date:  2016-05-03

7.  THE DISTRIBUTION, HISTOLOGIC PROFILE AND CLINICAL PRESENTATION OF GASTROINTESTINAL MALIGNANCIES IN LAGOS, NIGERIA.

Authors:  M Y Habeebu; O Salako; P T Okediji; B Mabadeje; O M Awofeso; A T Ajekigbe; F B Abdulkareem
Journal:  J West Afr Coll Surg       Date:  2017 Jan-Mar

8.  delGA (rs67491583) variant and colorectal cancer risk in an indigenous African population.

Authors:  T Ogundiran; S Tuupanen; L A Aaltonen; S Akarolo-Anthony; C Adebamowo
Journal:  Afr J Med Med Sci       Date:  2012-09

9.  Clinicopathological patterns and challenges of management of colorectal cancer in a resource-limited setting: a Tanzanian experience.

Authors:  Phillipo L Chalya; Mabula D McHembe; Joseph B Mabula; Peter F Rambau; Hyasinta Jaka; Mheta Koy; Eliasa Mkongo; Nestory Masalu
Journal:  World J Surg Oncol       Date:  2013-04-18       Impact factor: 2.754

  9 in total

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