Literature DB >> 11884582

Inhibition of hepatitis B virus replication by interferon requires proteasome activity.

Michael D Robek1, Stefan F Wieland, Francis V Chisari.   

Abstract

Hepatitis B virus (HBV) replication is inhibited in a noncytopathic manner by alpha/beta interferon (IFN-alpha/beta) and IFN-gamma. We demonstrate here that inhibitors of cellular proteasome activity can block this antiviral effect. These results suggest that a critical component of the IFN-induced antiviral response may be the proteasome-dependent degradation of viral or cellular proteins that are required for HBV replication.

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Year:  2002        PMID： 11884582      PMCID： PMC136040          DOI： 10.1128/jvi.76.7.3570-3574.2002

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  51 in total

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Review 2.  Ubiquitination and deubiquitination: targeting of proteins for degradation by the proteasome.

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Journal:  Semin Cell Dev Biol       Date:  2000-06       Impact factor: 7.727

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Authors:  S Goodbourn; L Didcock; R E Randall
Journal:  J Gen Virol       Date:  2000-10       Impact factor: 3.891

4.  Structural and functional characterization of interaction between hepatitis B virus X protein and the proteasome complex.

Authors:  Z Zhang; N Torii; A Furusaka; N Malayaman; Z Hu; T J Liang
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5.  Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules.

Authors:  K L Rock; C Gramm; L Rothstein; K Clark; R Stein; L Dick; D Hwang; A L Goldberg
Journal:  Cell       Date:  1994-09-09       Impact factor: 41.582

6.  Relative sensitivity of hepatitis B virus and other hepatotropic viruses to the antiviral effects of cytokines.

Authors:  H McClary; R Koch; F V Chisari; L G Guidotti
Journal:  J Virol       Date:  2000-03       Impact factor: 5.103

7.  Intrahepatic induction of alpha/beta interferon eliminates viral RNA-containing capsids in hepatitis B virus transgenic mice.

Authors:  S F Wieland; L G Guidotti; F V Chisari
Journal:  J Virol       Date:  2000-05       Impact factor: 5.103

8.  A gene in the chromosomal region 3p21 with greatly reduced expression in lung cancer is similar to the gene for ubiquitin-activating enzyme.

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Journal:  Proc Natl Acad Sci U S A       Date:  1993-07-01       Impact factor: 11.205

9.  Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin.

Authors:  G Fenteany; R F Standaert; W S Lane; S Choi; E J Corey; S L Schreiber
Journal:  Science       Date:  1995-05-05       Impact factor: 47.728

10.  Natural killer T cell activation inhibits hepatitis B virus replication in vivo.

Authors:  K Kakimi; L G Guidotti; Y Koezuka; F V Chisari
Journal:  J Exp Med       Date:  2000-10-02       Impact factor: 14.307
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  44 in total

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Journal:  World J Gastroenterol       Date:  2007-01-14       Impact factor: 5.742

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Journal:  J Virol       Date:  2011-08-24       Impact factor: 5.103

4.  Proteasomes regulate hepatitis B virus replication by degradation of viral core-related proteins in a two-step manner.

Authors:  Zi-Hua Zheng; Hui-Ying Yang; Lin Gu; Xiao-Mou Peng
Journal:  Virus Genes       Date:  2016-04-22       Impact factor: 2.332

5.  Inhibition of cellular proteasome activities mediates HBX-independent hepatitis B virus replication in vivo.

Authors:  Zhensheng Zhang; Eun Sun; Jing-hsiung James Ou; T Jake Liang
Journal:  J Virol       Date:  2010-06-30       Impact factor: 5.103

6.  Cytopathic and noncytopathic interferon responses in cells expressing hepatitis C virus subgenomic replicons.

Authors:  Ju-Tao Guo; Qing Zhu; Christoph Seeger
Journal:  J Virol       Date:  2003-10       Impact factor: 5.103

7.  Role of immunoproteasome catalytic subunits in the immune response to hepatitis B virus.

Authors:  Michael D Robek; Mayra L Garcia; Bryan S Boyd; Francis V Chisari
Journal:  J Virol       Date:  2006-11-01       Impact factor: 5.103

8.  Tumor necrosis factor activates a conserved innate antiviral response to hepatitis B virus that destabilizes nucleocapsids and reduces nuclear viral DNA.

Authors:  Robyn Puro; Robert J Schneider
Journal:  J Virol       Date:  2007-05-02       Impact factor: 5.103

9.  Inhibition of cellular proteasome activities enhances hepadnavirus replication in an HBX-dependent manner.

Authors:  Zhensheng Zhang; Ulrike Protzer; Zongyi Hu; James Jacob; T Jake Liang
Journal:  J Virol       Date:  2004-05       Impact factor: 5.103

10.  Bortezomib inhibits hepatitis B virus replication in transgenic mice.

Authors:  Prasanthi Bandi; Mayra L Garcia; Carmen J Booth; Francis V Chisari; Michael D Robek
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