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Literature DB >> 11884266

Obesity-related hypertension: role of the sympathetic nervous system, insulin, and leptin.

Abstract

Heightened sympathetic nervous system activity, hyperinsulinemia, insulin resistance, and hyperleptinemia contribute to obesity-related hypertension. However, the precise mechanism and sequence of events in this pathophysiologic event have not been clarified. This review concentrates on studies helping to clarify the mechanisms of blood pressure elevation associated with weight change, concentrating on the temporal changes in neuroendocrine factors that are known to control energy metabolism and blood pressure. A better understanding of the pathophysiologic mechanisms of obesity-related hypertension may help in prevention, treatment, and slowing of the cardiovascular complications of obesity.

Entities: Disease Gene

Mesh：

Substances：

Year: 2002 PMID： 11884266 DOI： 10.1007/s11906-002-0035-0

Source DB: PubMed Journal: Curr Hypertens Rep ISSN： 1522-6417 Impact factor: 5.369

52 in total

1. Weight gain-induced blood pressure elevation.

Authors: K Masuo; H Mikami; T Ogihara; M L Tuck
Journal: Hypertension Date: 2000-05 Impact factor: 10.190

2. Aerobic exercise training does not modify large-artery compliance in isolated systolic hypertension.

Authors: K E Ferrier; T K Waddell; C D Gatzka; J D Cameron; A M Dart; B A Kingwell
Journal: Hypertension Date: 2001-08 Impact factor: 10.190

3. Different mechanisms in weight loss-induced blood pressure reduction between a calorie-restricted diet and exercise.

Authors: Kazuko Masuo; Hiromi Rakugi; Toshio Ogihara; Gavin W Lambert
Journal: Hypertens Res Date: 2011-08-04 Impact factor: 3.872

4. Prevalence of hyperinsulinemia in young, nonobese Japanese men.

Authors: K Masuo; H Mikami; T Ogihara; M L Tuck
Journal: J Hypertens Date: 1997-02 Impact factor: 4.844

5. Dissociation of sympathetic nerve activity in arm and leg muscle during mental stress.

Authors: E A Anderson; B G Wallin; A L Mark
Journal: Hypertension Date: 1987-06 Impact factor: 10.190

6. Improvement of insulin sensitivity contributes to blood pressure reduction after weight loss in hypertensive subjects with obesity.

Authors: T Ikeda; T Gomi; N Hirawa; J Sakurai; N Yoshikawa
Journal: Hypertension Date: 1996-05 Impact factor: 10.190

7. Physical training and baroreceptor control of sympathetic nerve activity in humans.

Authors: G Grassi; G Seravalle; D A Calhoun; G Mancia
Journal: Hypertension Date: 1994-03 Impact factor: 10.190

8. Reductions in plasma catecholamines and blood pressure during weight loss in obese subjects.

Authors: M L Tuck; J R Sowers; L Dornfeld; L Whitfield; M Maxwell
Journal: Acta Endocrinol (Copenh) Date: 1983-02

9. Effect of insulin and glucose infusions on sympathetic nervous system activity in normal man.

Authors: J W Rowe; J B Young; K L Minaker; A L Stevens; J Pallotta; L Landsberg
Journal: Diabetes Date: 1981-03 Impact factor: 9.461

10. Role of the sympathetic nervous system in blood pressure maintenance in obesity.

Authors: J R Sowers; L A Whitfield; R A Catania; N Stern; M L Tuck; L Dornfeld; M Maxwell
Journal: J Clin Endocrinol Metab Date: 1982-06 Impact factor: 5.958

6 in total

Review 1. The role of the sympathetic nervous system in linking obesity with hypertension in white versus black Americans.

Authors: Pirooz Eslami; Michael Tuck
Journal: Curr Hypertens Rep Date: 2003-06 Impact factor: 5.369

2. Influence of resting energy expenditure on blood pressure is independent of body mass and a marker of sympathetic tone.

Authors: David W Brock; Connie L Tompkins; Gordon Fisher; Gary R Hunter
Journal: Metabolism Date: 2011-08-04 Impact factor: 8.694

6. Comparison of 6 equations for estimating glomerular filtration rate in a Chinese benign hypertensive nephrosclerosis population.

Authors: Guibao Ke; Zhibin Xie; Jie Xiao; Yamei Zhang; Yao Hu; Bohou Li; Nan Jiang; Xueqin Chen; Shuangxin Liu; Wei Shi
Journal: Medicine (Baltimore) Date: 2021-12-23 Impact factor: 1.817