Literature DB >> 1188362

Alpha-lactalbumin production in human mammary carcinoma.

H N Rose, C M McGrath.   

Abstract

Alpha-Lactalbumin was isolated from mature human milk and utilized as an immunogen in rabbits. A radioimmunoassay was developed that was capable of detecting nanogram quantities of the antigen. Alpha-Lactalbumin synthesis was detected in human breast cancer cells (MCF-7) cultivated as a continuous cell line in vitro. Other human carcinoma epithelial cell lines (throat and cervix) failed to react in this assay. The ability to synthesize alpha-lactalbumin by breast carcinoma cells appeared to be independent of the addition of prolactin to the culture medium.

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Year:  1975        PMID： 1188362     DOI： 10.1126/science.1188362

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  10 in total

1.  Angiogenin interacts with the plasminogen activation system at the cell surface of breast cancer cells to regulate plasmin formation and cell migration.

Authors:  Sujoy Dutta; Chirosree Bandyopadhyay; Virginie Bottero; Mohanan V Veettil; Lydia Wilson; Michael R Pins; Karen E Johnson; Case Warshall; Bala Chandran
Journal:  Mol Oncol       Date:  2014-01-04       Impact factor: 6.603

2.  A 23-pS Ca2(+)-activated K+ channel in MCF-7 human breast carcinoma cells: an apparent correlation of channel incidence with the rate of cell proliferation.

Authors:  E A Wegman; J A Young; D I Cook
Journal:  Pflugers Arch       Date:  1991-02       Impact factor: 3.657

3.  Enhancement of mechanisms acting against mammary carcinoma: pancreatic trypsin inhibitor.

Authors:  A A Hakim
Journal:  Klin Wochenschr       Date:  1978-08-01

4.  Factors affecting protein composition of breast secretions from nonlactating women.

Authors:  F Vizoso; L M Sánchez; I Díez-Itza; M Luz Lamelas; C López-Otín
Journal:  Breast Cancer Res Treat       Date:  1992       Impact factor: 4.872

5.  Hormone responsive human breast cancer in long-term tissue culture: effect of insulin.

Authors:  C K Osborne; G Bolan; M E Monaco; M E Lippman
Journal:  Proc Natl Acad Sci U S A       Date:  1976-12       Impact factor: 11.205

6.  Hormonal effects on intracellular and secreted casein in cultures of mouse mammary epithelial cells on floating collagen membranes.

Authors:  J T Emerman; J Enami; D R Pitelka; S Nandi
Journal:  Proc Natl Acad Sci U S A       Date:  1977-10       Impact factor: 11.205

7.  Hormone sensitivity of gynecological tumor cells in tissue culture.

Authors:  W E Simon; F Hölzel
Journal:  J Cancer Res Clin Oncol       Date:  1979-07-27       Impact factor: 4.553

8.  Effect of sodium butyrate on synthesis of specific proteins by human breast-carcinoma cells.

Authors:  R J Grieve; K L Woods; P R Mann; S C Smith; G D Wilson; A Howell
Journal:  Br J Cancer       Date:  1980-10       Impact factor: 7.640

9.  Molecular evolution of versatile derivatives from a GFP-like protein in the marine copepod Chiridius poppei.

Authors:  Akihisa Shimizu; Ikuo Shiratori; Katsunori Horii; Iwao Waga
Journal:  PLoS One       Date:  2017-07-11       Impact factor: 3.240

10.  Interactions between exosomes from breast cancer cells and primary mammary epithelial cells leads to generation of reactive oxygen species which induce DNA damage response, stabilization of p53 and autophagy in epithelial cells.

Authors:  Sujoy Dutta; Case Warshall; Chirosree Bandyopadhyay; Dipanjan Dutta; Bala Chandran
Journal:  PLoS One       Date:  2014-05-15       Impact factor: 3.240
  10 in total

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