| Literature DB >> 11881746 |
M Vila1, D C Wu, S Przedborski.
Abstract
The development of new methods for manipulating the animal genome by transgenic and gene-targeting technologies provides a unique means of studying the most intimate aspects of countless human diseases, including Parkinson's disease (PD). In this review, the contribution of such engineered models to our current understanding of the pathophysiology, etiology and pathogenesis of PD will be discussed.Entities:
Mesh：
Year: 2001 PMID： 11881746 DOI： 10.1016/s0166-2236(00)01984-6
Source DB: PubMed Journal: Trends Neurosci ISSN： 0166-2236 Impact factor: 13.837