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Literature DB >> 11880452

Successful outcome of treatment of a disseminated infection due to Fusarium dimerum in a leukemia patient.

Valérie Letscher-Bru¹, France Campos, Jocelyn Waller, Raoul Randriamahazaka, Ermanno Candolfi, Raoul Herbrecht.

Abstract

We report the first case of proven disseminated infection due to Fusarium dimerum associated with a favorable outcome in a patient with acute leukemia and prolonged neutropenia. The patient presented persistent fever, multiple necrotic skin lesions, and bilateral pneumopathy. F. dimerum was first isolated from three blood cultures and then from a skin biopsy and a mouth wash. Microscopy of positive blood cultures showed hyphae with phialides and few curved unicellular and some rare bicellular phialoconidia, permitting immediate presumptive identification of the genus FUSARIUM: The patient failed to respond to conventional amphotericin B but recovered after treatment was switched to amphotericin B-lipid complex and neutrophil recovery.

Entities: Chemical Disease Species

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Year: 2002 PMID： 11880452 PMCID： PMC120274 DOI： 10.1128/JCM.40.3.1100-1102.2002

Source DB: PubMed Journal: J Clin Microbiol ISSN： 0095-1137 Impact factor: 5.948

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