Literature DB >> 11880184

CASK and its target gene Reelin were co-upregulated in human esophageal carcinoma.

Qun Wang1, Jiayun Lu, Cuihong Yang, Xiuqin Wang, Lu Cheng, Gengxi Hu, Yuntian Sun, Xun Zhang, Min Wu, Zhihua Liu.   

Abstract

Calcium/calmodulin-dependent serine protein kinase (CASK) showed overexpression in human esophageal carcinoma by suppression subtractive hybridization. The upregulation of CASK gene and its target gene Reelin in human esophageal carcinoma tissues versus corresponding normal tissues was revealed by reverse transcription polymerase chain reaction (RT-PCR), immunohistochemistry or Western blot. Moreover, RT-PCR results indicated that the expression patterns of CASK and Reelin in human gastric carcinoma and colon carcinoma were different with those in esophageal carcinoma. Therefore, it suggested that CASK and Reelin were associated with tumorigenesis of esophagus and they were co-upregulated in human esophageal carcinoma.

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Year:  2002        PMID： 11880184     DOI： 10.1016/s0304-3835(01)00846-1

Source DB:  PubMed          Journal:  Cancer Lett        ISSN： 0304-3835            Impact factor:   8.679


  21 in total

1.  Evolution of CASK into a Mg2+-sensitive kinase.

Authors:  Konark Mukherjee; Manu Sharma; Reinhard Jahn; Markus C Wahl; Thomas C Südhof
Journal:  Sci Signal       Date:  2010-04-27       Impact factor: 8.192

2.  The Effect of hsa-miR-451b Knockdown on Biological Functions of Gastric Cancer Stem-Like Cells.

Authors:  Diba Borzabadi Farahani; Hassan Akrami; Behrouz Moradi; Kiumars Mehdizadeh; Mohammad Reza Fattahi
Journal:  Biochem Genet       Date:  2021-03-16       Impact factor: 1.890

Review 3.  Cancer models in Caenorhabditis elegans.

Authors:  Natalia V Kirienko; Kumaran Mani; David S Fay
Journal:  Dev Dyn       Date:  2010-05       Impact factor: 3.780

4.  Overexpression of Plk1 promotes malignant progress in human esophageal squamous cell carcinoma.

Authors:  Chunling Zhao; Lei Gong; Wentong Li; Limei Chen
Journal:  J Cancer Res Clin Oncol       Date:  2010-01       Impact factor: 4.553

5.  High expression of CASK correlates with progression and poor prognosis of colorectal cancer.

Authors:  Jin-Lai Wei; Zhong-Xue Fu; Min Fang; Qiu-Yuan Zhou; Qing-Ning Zhao; Jin-Bao Guo; Wei-Dong Lu; Hao Wang
Journal:  Tumour Biol       Date:  2014-06-14

6.  Reelin Deficiency Delays Mammary Tumor Growth and Metastatic Progression.

Authors:  Elvira Khialeeva; Joan W Chou; Denise E Allen; Alec M Chiu; Steven J Bensinger; Ellen M Carpenter
Journal:  J Mammary Gland Biol Neoplasia       Date:  2017-01-26       Impact factor: 2.673

Review 7.  Neurochemical Markers in the Mammalian Brain: Structure, Roles in Synaptic Communication, and Pharmacological Relevance.

Authors:  Christopher L Rees; Charise M White; Giorgio A Ascoli
Journal:  Curr Med Chem       Date:  2017       Impact factor: 4.530

8.  Reelin is involved in transforming growth factor-β1-induced cell migration in esophageal carcinoma cells.

Authors:  Yi Yuan; Hongyan Chen; Gang Ma; Xiaofeng Cao; Zhihua Liu
Journal:  PLoS One       Date:  2012-02-29       Impact factor: 3.240

9.  TARGETgene: a tool for identification of potential therapeutic targets in cancer.

Authors:  Chia-Chin Wu; David D'Argenio; Shahab Asgharzadeh; Timothy Triche
Journal:  PLoS One       Date:  2012-08-31       Impact factor: 3.240

10.  Long Noncoding RNA AATBC Promotes the Proliferation and Migration of Prostate Cancer Cell Through miR-1245b-5p/CASK Axis.

Authors:  Wenyuan Zhang; Qionghong Liu; Jun Zhao; Tiejun Wang; Jinshan Wang
Journal:  Cancer Manag Res       Date:  2021-06-28       Impact factor: 3.989
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