Literature DB >> 11880054

Structured treatment interruptions in HIV/AIDS therapy.

Julianna Lisziewicz1, Franco Lori.   

Abstract

Structured treatment interruption (STI) has been investigated for three distinct clinical scenarios: during acute infection with the goal of immune reconstitution and auto immunization; during chronic infection, to decrease the amount and toxicity of antiretroviral drugs; and during virologic failure to restore response to subsequent antiretroviral therapy. The potential costs and benefits of STI should be determined.

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Year:  2002        PMID： 11880054     DOI： 10.1016/s1286-4579(01)01529-5

Source DB:  PubMed          Journal:  Microbes Infect        ISSN： 1286-4579            Impact factor:   2.700


  5 in total

1.  Customizing treatment to the patient: adaptive treatment strategies.

Authors:  Susan A Murphy; L M Collins; A John Rush
Journal:  Drug Alcohol Depend       Date:  2007-03-09       Impact factor: 4.492

Review 2.  Cellular reservoirs of HIV-1 and their role in viral persistence.

Authors:  Aikaterini Alexaki; Yujie Liu; Brian Wigdahl
Journal:  Curr HIV Res       Date:  2008-09       Impact factor: 1.581

3.  Boosting immunity by antiviral drug therapy: a simple relationship among timing, efficacy, and success.

Authors:  Natalia L Komarova; Eleanor Barnes; Paul Klenerman; Dominik Wodarz
Journal:  Proc Natl Acad Sci U S A       Date:  2003-02-06       Impact factor: 11.205

4.  Immunological and virological consequences of patient-directed antiretroviral therapy interruption during chronic HIV-1 infection.

Authors:  C T Burton; M R Nelson; P Hay; B G Gazzard; F M Gotch; N Imami
Journal:  Clin Exp Immunol       Date:  2005-11       Impact factor: 4.330

5.  In Silico Modeling in Infectious Disease.

Authors:  Silvia Daun; Gilles Clermont
Journal:  Drug Discov Today Dis Models       Date:  2007-10-01
  5 in total

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