| Literature DB >> 11880052 |
Vivek K Arora1, Brenda L Fredericksen, J Victor Garcia.
Abstract
Primate lentiviruses encode a small protein designated Nef that has been shown to be a major determinant of virus pathogenicity. Nef regulates multiple host factors in order to optimize the cellular environment for virus replication. The mechanisms by which this small protein modulates distinct host cell properties provide intriguing insight into the intricate interaction between virus and host.Entities:
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Year: 2002 PMID： 11880052 DOI： 10.1016/s1286-4579(01)01527-1
Source DB: PubMed Journal: Microbes Infect ISSN： 1286-4579 Impact factor: 2.700