Literature DB >> 1187962

Chlorpromazine effects on brain activity (contingent negative variation) and reaction time in normal women.

J J Tecce, J O Cole, J Savignano-Bowman.   

Abstract

Electrical brain activity (contingent negative variation of CNV) and psychomotor behavior (reaction time or RT) were measured after 50 mg of chlorpromazine (CPZ) or placebo were given orally to 28 normal women. CPZ reduced CNV 2 and 3 hrs post-drug and slowed RT 3 hrs post-drug. CNV amplitude appears to be an accurate indicator of drug-produced changes in alertness.

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Year:  1975        PMID： 1187962     DOI： 10.1007/bf00429268

Source DB:  PubMed          Journal:  Psychopharmacologia


  7 in total

1.  A comparison of some physiological and psychological effects of propranolol and diazepam in normal subjects.

Authors:  H Ashton; J E Millman; R Telford; J W Thompson
Journal:  Br J Clin Pharmacol       Date:  1976-08       Impact factor: 4.335

2.  Psychopharmacological and endocrinological effects of melanocyte stimulating hormones in normal man.

Authors:  H Ashton; J E Millman; R Telford; J W Thompson; T F Davies; R Hall; S Shuster; A J Thody; D H Coy; A J Kastin
Journal:  Psychopharmacology (Berl)       Date:  1977-12-19       Impact factor: 4.530

3.  Biphasic dose-related responses of the CNV (contingent negative variation) to I.V. nicotine in man.

Authors:  H Ashton; V R Marsh; J E Millman; M D Rawlins; R Telford; J W Thompson
Journal:  Br J Clin Pharmacol       Date:  1980-12       Impact factor: 4.335

4.  Central nervous system depressant actions of clonidine and UK-14,304: partial dissociation of EEG and behavioural effects.

Authors:  H Ashton; M D Rawlins
Journal:  Br J Clin Pharmacol       Date:  1978-02       Impact factor: 4.335

5.  A comparison of the central nervous system effects of haloperidol, chlorpromazine and sulpiride in normal volunteers.

Authors:  G R McClelland; S M Cooper; A J Pilgrim
Journal:  Br J Clin Pharmacol       Date:  1990-12       Impact factor: 4.335

6.  A comparison of some physiological and psychological effects of Motival (fluphenazine and nortriptyline) and diazepam in normal subjects.

Authors:  H Ashton; J E Millman; R Telford; J W Thompson
Journal:  Br J Clin Pharmacol       Date:  1978-02       Impact factor: 4.335

7.  Contingent negative variation as a dopaminergic biomarker: evidence from dose-related effects of methylphenidate.

Authors:  Anke M W Linssen; Eric F P M Vuurman; Anke Sambeth; Stephane Nave; Will Spooren; Gabriel Vargas; Luca Santarelli; Wim J Riedel
Journal:  Psychopharmacology (Berl)       Date:  2011-05-20       Impact factor: 4.530
  7 in total

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