Literature DB >> 11878

Pyrophosphatase and ATPase of isolated cartilage matrix vesicles.

R Felix, H Fleisch.   

Abstract

Some of the characteristics of the pyrophosphatase and ATPase activities studied in isolated cartilage matrix vesicles were found to be similar to those already reported for the solubilized and purified bone alkaline phosphatase. Thus, the pH optimum of the pyrophosphatase activity responded similarly to changes in the concentration of Mg2+, Ca2+, and PPi. Further, the ATPase activity was not activated by Ca2+ in the presence of an optimal Mg2+ concentration. It is proposed that a function of the alkaline phosphatase of matrix vesicles in vivo is to hydrolyze the substrates PPi, ADP, and ATP, which are known inhibitors of calcium phosphate precipitation.

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Year:  1976        PMID： 11878     DOI： 10.1007/BF02010340

Source DB:  PubMed          Journal:  Calcif Tissue Res        ISSN： 0008-0594


  14 in total

1.  An improved method for the micro-determination of inorganic phosphate in small volumes of biological fluids.

Authors:  R J HALL
Journal:  J Med Lab Technol       Date:  1963-04

2.  Mechanisms of calcification: role of collagen, polyphosphates, and phosphatase.

Authors:  H FLEISH; W F NEUMAN
Journal:  Am J Physiol       Date:  1961-06

3.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

4.  Relation between alkaline phosphatase and Ca 2+ -ATPase in calcium transport.

Authors:  R G Russell; A Monod; J P Bonjour; H Fleisch
Journal:  Nat New Biol       Date:  1972-11-22

5.  Induction of intestinal brush border alkaline phosphatase by vitamin D and identity with ca-ATPase.

Authors:  M Haussler; L A Nagode; H Rasmussen
Journal:  Nature       Date:  1970-12-19       Impact factor: 49.962

6.  Electron microscopie and enzyme cytochemical studies on the guinia pig metaphysis with special reference to the lysosomal system of different cell types.

Authors:  J Thyberg; S Nilsson; U Friberg
Journal:  Cell Tissue Res       Date:  1975       Impact factor: 5.249

7.  Inorganic pyrophosphate in plasma in normal persons and in patients with hypophosphatasia, osteogenesis imperfecta, and other disorders of bone.

Authors:  R G Russell; S Bisaz; A Donath; D B Morgan; H Fleisch
Journal:  J Clin Invest       Date:  1971-05       Impact factor: 14.808

8.  Isolation and characterization of calcifying matrix vesicles from epiphyseal cartilage.

Authors:  S Y Ali; S W Sajdera; H C Anderson
Journal:  Proc Natl Acad Sci U S A       Date:  1970-11       Impact factor: 11.205

9.  Influence of dichloromethylene diphosphonate (Cl2MDP) and calcitonin on bone resorption, lactate production and phosphatase and pyrophosphatase content of mouse calvaria treated with parathyroid hormone in vitro.

Authors:  D B Morgan; A Monod; R G Russel; H Fleisch
Journal:  Calcif Tissue Res       Date:  1973-12-31

10.  Vesicles associated with calcification in the matrix of epiphyseal cartilage.

Authors:  H C Anderson
Journal:  J Cell Biol       Date:  1969-04       Impact factor: 10.539
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  25 in total

1.  Enzymatic properties of the Ca2+-binding glycoprotein isolated from preosseous cartilage.

Authors:  N Stagni; G Furlan; F Vittur; M Zanetti; B de Bernard
Journal:  Calcif Tissue Int       Date:  1979-11       Impact factor: 4.333

2.  Localization of phosphatidylserine in isolated chick epiphyseal cartilage matrix vesicles with trinitrobenzenesulfonate.

Authors:  R J Majeska; D L Holwerda; R E Wuthier
Journal:  Calcif Tissue Int       Date:  1979-03-13       Impact factor: 4.333

3.  Matrix vesicles are enriched in metalloproteinases that degrade proteoglycans.

Authors:  D D Dean; Z Schwartz; O E Muniz; R Gomez; L D Swain; D S Howell; B D Boyan
Journal:  Calcif Tissue Int       Date:  1992-04       Impact factor: 4.333

4.  Rat osseous plate alkaline phosphatase: effect of neutral protease digestion on the hydrolysis of pyrophosphate and nitrophenylphosphate.

Authors:  Rúbia R Gonçalves; Rosa P M Furriel; João A Jorge; Francisco A Leone
Journal:  Mol Cell Biochem       Date:  2002-12       Impact factor: 3.396

5.  Developmental pattern of alkaline phosphatase in soluble and particulate fractions of rat skull cap and femur.

Authors:  G P Murthy; R Rajalakshmi; C V Ramakrishnan
Journal:  Calcif Tissue Int       Date:  1986-09       Impact factor: 4.333

6.  A comparison of Ca2+-, Mg2+-ATPase and alkaline phosphatase activities of rat incisor pulp.

Authors:  M K Guo; H H Messer
Journal:  Calcif Tissue Res       Date:  1978-11-10

7.  Ultrastructural localization of alkaline phosphatase in the hypertrophic chondrocyte of the frog.

Authors:  G R Dickson
Journal:  Histochemistry       Date:  1978-09-28

8.  Partition of inorganic ions and phospholipids in isolated cell, membrane and matrix vesicle fractions: evidence for Ca-Pi-acidic phospholipid complexes.

Authors:  R E Wuthier; S T Gore
Journal:  Calcif Tissue Res       Date:  1977-12-28

9.  Increase in alkaline phosphatase activity in calvaria cells cultured with diphosphonates.

Authors:  R Felix; H Fleisch
Journal:  Biochem J       Date:  1979-10-01       Impact factor: 3.857

10.  Adsorption and mineralization effects of citrate and phosphocitrate on hydroxyapatite.

Authors:  M Johnsson; C F Richardson; J D Sallis; G H Nancollas
Journal:  Calcif Tissue Int       Date:  1991-08       Impact factor: 4.333
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